Mekam Capsule (Meloxicam)

Adult dose

1. Acute exacerbation of osteoarthritis (degenerative arthritis): ○ Adults: Administer meloxicam 7.5 mg orally once daily. If symptoms do not improve, the dose may be increased to 15 mg per day as needed. 2. Rheumatoid arthritis, ankylosing spondylitis: ○ Adults: Administer 15 mg of this drug orally once daily. The dose may be reduced to 7.5 mg per day according to response to treatment. This drug should not be administered at doses exceeding 15 mg per day and should be taken with water or another beverage during a meal. ○ In older adults or those at increased risk of adverse reactions, treatment is usually started at a dose of 7.5 mg per day. ○ Patients with severe renal failure receiving hemodialysis should not receive more than 7.5 mg per day.

This medication may cause gastrointestinal bleeding in those who regularly consume more than three glasses of alcohol daily, so it must be discussed with a physician or pharmacist. This medication can increase the risk of cardiovascular diseases, and serious issues such as myocardial infarction or stroke may occur, so patients with a history of cardiovascular disease or risk factors should be monitored carefully. This medication may cause serious adverse reactions such as gastrointestinal bleeding, ulcers, or perforations, so caution should be exercised, especially in patients with a history of gastrointestinal diseases or the elderly. Rarely, this medication can cause serious skin reactions or life-threatening hypersensitive reactions, so if symptoms such as skin rash or mucosal damage occur, discontinuation should be immediate. This medication may affect kidney function and may lead to kidney diseases such as interstitial nephritis or nephrotic syndrome, so patients with impaired kidney function should use it cautiously. Liver function tests may temporarily increase, so if any signs of liver dysfunction appear, this medication should be discontinued and appropriate tests should be performed. This medication may reduce fertility, so women planning to become pregnant should avoid it, as should pregnant or breastfeeding women. It should not be administered to individuals allergic to aspirin or other non-steroidal anti-inflammatory drugs, those with a history of gastrointestinal bleeding or ulcers, or patients with severe liver or kidney diseases. Elderly patients, individuals with a history of gastrointestinal diseases, and patients at risk for cardiovascular diseases should be monitored more closely when using this medication. During the course of taking this medication, regular blood tests, liver function tests, and kidney function tests should be performed to detect and respond to adverse reactions promptly. When taken with other medications, interactions may occur; thus, inform a physician or pharmacist, especially when taking anticoagulants, diuretics, antihypertensive medications, lithium, or methotrexate. This medication should never be taken during pregnancy as it may severely affect the fetus, and it should also be avoided while breastfeeding. In cases of overdose, one should immediately go to the hospital for gastric lavage and appropriate treatment, and since there is no antidote for this medication, caution is advised. This medication should be kept out of the reach of children and stored in its original container with the lid tightly closed.

Gastrointestinal bleeding, significant cardiovascular thrombotic reaction, myocardial infarction, stroke, hemorrhage of the stomach or intestines, ulcer, perforation, exfoliative dermatitis, mucocutaneous syndrome, toxic epidermal necrolysis, anaphylactic reaction, interstitial nephritis, glomerulonephritis, renal medullary necrosis, nephrotic syndrome, elevated serum transaminases, elevated liver function tests, increased plasma creatinine, increased blood urea nitrogen, aplastic anemia, bone marrow suppression, changes in blood cell counts, leukopenia, thrombocytopenia, anemia, decreased plasma iron, decreased hemoglobin, decreased hematocrit level, increased neutrophils, increased eosinophils, increased basophils, increased monocytes, agranulocytosis, anaphylaxis, anaphylactic-like reaction, discomfort, confusion, loss of sense of direction, mood changes, mood disorders, insomnia, nightmares, anxiety, increased appetite, depression, nervousness, dizziness, drowsiness, headache, head pressure, fatigue, lethargy, taste dysfunction, mental confusion, convulsions, sensory disturbances, tremors, visual blurriness, visual impairment, conjunctivitis, foreign body sensation in the eye, hemorrhage of the sclera, tinnitus, palpitations, increased blood pressure, flushing, facial flushing, arrhythmia, tachycardia, hypotension, hypertension, myocardial infarction, angina, heart failure, vasculitis, cough, upper respiratory infection, asthma, bronchospasm, difficulty breathing, dyspepsia, nausea, vomiting, abdominal pain, constipation, bloating, diarrhea, loss of appetite, peptic ulcer, occult gastrointestinal bleeding, overt gastrointestinal bleeding, stomatitis, gastritis, esophagitis, belching, dry mouth, thirst, cheilitis, occult blood in stool, gastrointestinal perforation, colitis, pancreatitis, melena, perforated peptic ulcer, hepatitis, jaundice, liver failure, alopecia, increased sweating, skin rash, urticaria, angioedema, vesicular dermatitis, erythema multiforme, photosensitivity reactions, contact dermatitis, fixed drug eruption, urinary retention, changes in kidney function tests, decreased total protein, decreased albumin, proteinuria, glycosuria, increased urine sediment, hematuria, sodium and water retention, hyperkalemia, acute renal failure, decreased urine output, frequent urination, urinary tract infection, interstitial nephritis, edema, lower limb edema, malaise, fever, facial edema, syncope, weight loss, weight gain, breast and axillary pain, arthralgia, low back pain, axillary and chest pain, rigidity, lower limb weakness, decreased female reproductive ability, dehydration, drowsiness, nausea, vomiting, epigastric pain, hypertension, acute renal failure, liver failure, respiratory depression, coma, convulsions, cardiovascular collapse, cardiac arrest

This medication is sensitive to light and should be stored in a container that blocks light. Additionally, it should be stored at room temperature between 1 to 30 degrees Celsius to maintain effectiveness.

Appearance

Capsule preparation with light yellow powder in a green and dark green capsule.

Package unit

30 capsules/bottle, 200 capsules/bottle