Medication info

Carvedilol Tablet (Carvedilol)

Prescription medicationTabletOralExpired
Ingredient · strength
Carvedilol›25mg / 1 tablet
Manufacturer / importer
Sama Pharmaceutical Co., Ltd.
Appearance
White round tablet
Packaging
100 tablets (10 tablets/PTP x 10)
Approval status
Expired

MFDS item code 200400787 · Notified 2004.05.11

This product's status changed to Expired on 2024.07.01. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Adjunctive treatment of congestive heart failure, essential hypertension, and chronic stable angina
Who takes it
Adults
Adult dose
Do not increase the dose or stop taking this medicine without your doctor's instructions. 1. Essential hypertension 1) Adults (1) For the first two days, administer 12.5 mg of carvedilol orally once daily, then administer 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is necessary, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Older adults For some older adults, 12.5 mg once daily may provide sufficient effect. However, if the effect is insufficient after 2 weeks of treatment, the dose may be increased. 2. Chronic stable angina 1) For the first two days, administer 12.5 mg of this medicine per dose orally twice daily, then administer 25 mg per dose orally twice daily. 2) The usual dose is 25 mg per dose twice daily for 2 weeks. If an increase is needed (excluding older adults), the dose may be increased to 50 mg per dose twice daily. 3. Congestive heart failure 1) The initial treatment is generally 3.125 mg of this medicine per dose orally twice daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg per dose twice daily for 2 weeks, then increase to 12.5 mg per dose twice daily for 2 weeks, and then increase to 25 mg per dose twice daily. 2) After taking each dose for at least 2 weeks, increase the dose gradually to the maximum dose tolerated by the patient. 3) The minimum effective dose is 6.25 mg per dose twice daily. The maximum dose is 25 mg per dose twice daily for patients weighing 85 kg or less, and 50 mg per dose twice daily for patients weighing more than 85 kg. 4) To control the rate of absorption, it is recommended to take this medicine with meals in the morning and evening. Taking it with meals slows the rate of absorption and may reduce the incidence of orthostatic hypotension.

Ingredients

Manufacturer
Sama Pharmaceutical Co., Ltd.

Efficacy & effects

Adjunctive treatment of congestive heart failure, essential hypertension, and chronic stable angina

  • Essential hypertension
  • chronic stable angina
  • congestive heart failure
View approved original text

This medication is used for cardiovascular diseases such as essential hypertension, chronic stable angina, and congestive heart failure. It is particularly helpful as an adjunct to diuretics, digitalis preparations, ACE inhibitors, and other vasodilators. It aids in controlling the patient's blood pressure and improving heart function, and it is useful in alleviating symptoms of heart failure. It is used to effectively manage cardiovascular health.

How to take

Adult dose

Do not increase the dose or stop taking this medicine without your doctor's instructions. 1. Essential hypertension 1) Adults (1) For the first two days, administer 12.5 mg of carvedilol orally once daily, then administer 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is necessary, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Older adults For some older adults, 12.5 mg once daily may provide sufficient effect. However, if the effect is insufficient after 2 weeks of treatment, the dose may be increased. 2. Chronic stable angina 1) For the first two days, administer 12.5 mg of this medicine per dose orally twice daily, then administer 25 mg per dose orally twice daily. 2) The usual dose is 25 mg per dose twice daily for 2 weeks. If an increase is needed (excluding older adults), the dose may be increased to 50 mg per dose twice daily. 3. Congestive heart failure 1) The initial treatment is generally 3.125 mg of this medicine per dose orally twice daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg per dose twice daily for 2 weeks, then increase to 12.5 mg per dose twice daily for 2 weeks, and then increase to 25 mg per dose twice daily. 2) After taking each dose for at least 2 weeks, increase the dose gradually to the maximum dose tolerated by the patient. 3) The minimum effective dose is 6.25 mg per dose twice daily. The maximum dose is 25 mg per dose twice daily for patients weighing 85 kg or less, and 50 mg per dose twice daily for patients weighing more than 85 kg. 4) To control the rate of absorption, it is recommended to take this medicine with meals in the morning and evening. Taking it with meals slows the rate of absorption and may reduce the incidence of orthostatic hypotension.

Precautions

This medication should often not be used in certain patients. For example, individuals allergic to this medication or its components, those with severely impaired heart function, those with extremely slow heart rates, those with heart conduction issues, individuals with heart diseases related to the lungs, those with severe metabolic problems due to diabetes, and those with respiratory diseases such as asthma or chronic obstructive pulmonary disease may be at risk to their health from taking this medication. Additionally, women who are pregnant or may become pregnant, nursing mothers, patients with severe liver dysfunction, and individuals with peripheral blood circulation disorders should not be administered this medication. Patients with diabetes, those with a history of allergic reactions, patients with unstable heart function, individuals with reduced kidney function, and the elderly should be especially cautious when taking this medication. During treatment, various side effects such as dizziness, fatigue, headache, decreased heart rate, lowered blood pressure, worsening heart failure symptoms, gastrointestinal symptoms, skin rashes, liver function abnormalities may occur. If any symptoms arise, immediate consultation with a doctor is advised. Long-term use of this medication requires regular checks of heart function, blood pressure, heart rate, etc., and suddenly stopping the medication may worsen heart disease symptoms; dosage should be gradually reduced according to a doctor's instructions. Moreover, interactions may occur when taken with other medications, so it is essential to inform the doctor or pharmacist about all medications being taken and manage them carefully. During pregnancy or breastfeeding, this medication should not be taken as it may be harmful to the fetus or newborn, and safety in children or adolescents under 18 years has not been established. The elderly may have elevated drug concentrations due to decreased liver function, so starting from a lower dose and closely monitoring the condition is recommended. In cases of overdose, severe symptoms such as decreased blood pressure, heart rate reduction, and decreased heart function may occur, so immediate contact with a medical institution for appropriate treatment is necessary. This medication may discolor when exposed to light, so it should be stored in a light-resistant sealed container, kept out of reach of children, and should not be transferred to another container.

Side effects

  • Dizziness
  • headache
  • fatigue
  • weakness
  • hallucinations
  • confusion
  • depression
  • sleep disturbances
  • nightmares
  • psychosis
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  • severe bradycardia
  • shock
  • complete atrioventricular block
  • heart failure
  • cardiac arrest
  • hypotension
  • loss of consciousness
  • decreased pulse rate
  • cold extremities
  • edema
  • respiratory arrest
  • worsening renal function
  • renal failure
  • increased airway resistance
  • nausea
  • diarrhea
  • abdominal pain
  • vomiting
  • constipation
  • urticaria
  • itching
  • lichenoid reaction
  • hyperhidrosis
  • allergic rash
  • thrombocytopenia
  • leukopenia
  • hypoglycemia
  • masking of hyperthyroid function
  • hyperglycemia
  • weight gain
  • increased serum cholesterol
  • bradycardia
  • hypotension
  • shortness of breath
  • hypertension in angina
  • liver dysfunction
  • jaundice
  • limb pain
  • decreased tears
  • sensory disturbances
  • visual disturbances
  • eye irritation
  • dry mouth
  • urinary disorders
  • sexual dysfunction
  • allergic reactions
  • toxic epidermal necrolysis
  • Stevens-Johnson syndrome
  • hypotension
  • myocardial weakness
  • respiratory arrest
  • dyspnea
  • bronchospasm
  • disturbance of consciousness
  • generalized seizure

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light, so it should be stored in a sealed container that blocks light. Additionally, it is advisable to store the medication at room temperature between 1 degree and 30 degrees.

Appearance and packaging

Appearance

White round tablet

Package unit

100 tablets (10 tablets/PTP x 10)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.