Uni-Infusion Injection (L-Aspartic Acid-L-Ornithine)

Adult dosage

For hepatic encephalopathy (including pre-coma and coma), L-Aspartic Acid-L-Ornithine can be mixed up to 40 g (8 ampoules) in appropriate intravenous fluids and administered as a drip infusion daily. The dosage may be adjusted appropriately according to the symptoms.

This medication is in a glass ampoule and can have glass fragments enter the solution when opening the container, so it should be cut carefully to minimize glass particles. Extra caution should be taken especially when used for children or the elderly. This medication should not be used in patients with certain conditions. For example, it should not be administered to patients with lactate acidosis, methanol poisoning, sensitivities to fructose or sorbitol, certain enzyme deficiencies, and severely impaired renal function. Additionally, this medication contains sodium metabisulfite, which may cause allergic reactions. Patients with asthma or those who are sensitive to sulfites may experience severe allergic reactions, so it should be used with caution. When using this medication, there may occasionally be a feeling of warmth in the back of the head or nausea, and gastrointestinal discomfort or vomiting may occur. In case of high dosages, urea levels in the blood or urine should be monitored to check the body condition. Patients with weakened liver function should adjust the infusion speed to reduce discomfort or vomiting. This medication should be administered slowly intravenously, as rapid infusion may lead to side effects. When storing it, it should be kept in a secure place out of reach of children and should not be transferred from its original container to another container. This will help maintain the quality of the medication and prevent misuse.

Serious side effects

Asthma attack

Mild side effects

• Warm sensation in the back of the head
• nausea
• gastrointestinal discomfort
• vomiting

This medication may be sensitive to light, so it should be stored in a light-protected tightly sealed container. Additionally, the medication should be stored at room temperature between 1 to 30 degrees Celsius. Storing it this way will help maintain the effectiveness of the medication over a long period.

Appearance

[For domestic use, for export 1] Colorless to light yellow solution contained in a brown ampoule

Package unit

5 ampoules/box [(10 milliliters/ampoule)], 10 ampoules/box [(10 milliliters/ampoule)], 25 ampoules/box [(10 milliliters/ampoule)]