Gelasol Injection

Adult dosage

When administered peripherally, generally, 200 to 400 mL is dripped. The administration rate is approximately 120 minutes for 200 mL (approximately 25 drops per minute), and a total amino acid amount of about 10 g over 60 minutes is desirable for utilization in the body. When administered centrally, generally, 400 to 800 mL is continuously administered through central venous catheter using high-calorie fluid therapy per day. The dosage should be adjusted according to age, symptoms, and weight.

Children's dosage

When administered peripherally, it should be administered slowly to children.

This medication must be used according to a physician's instructions. It should not be used in patients with hepatic coma or those at risk of hepatic coma. Patients with severe renal impairment or elevated blood nitrogen levels should also not be administered this medication. Use should be avoided in patients with problems in nitrogen metabolism, those with wasting heart failure, or pulmonary edema. It should not be administered to patients with oliguria (very low urine output) or anuria (no urine output). If it contains sodium or chloride ions, it is contraindicated in patients with hypernatremia, hyperchloremia, or alkalosis. In patients with severe acidosis, congestive heart failure, or edema due to sodium retention, it should be administered with caution. Patients with elevated potassium levels or potassium retention should also be cautious, and use should be carefully monitored in patients with liver and kidney dysfunction. Since it contains sodium bisulfite, there is a risk of allergic reactions or asthma attacks in some patients, especially those with asthma. This medication may rarely cause hypersensitivity reactions like skin rashes, so administration should be stopped immediately if symptoms occur. Gastrointestinal symptoms such as nausea and vomiting, chest discomfort, palpitations, rapid heartbeat, and elevated blood pressure may occasionally occur. Rapid administration of large doses may result in acidosis. Various adverse reactions, including chills, fever, headache, difficulty in breathing, shock, bronchospasm, urinary spasms, may occur. Metabolic complications such as metabolic acidosis, hypophosphatemia, alkalosis, hyperglycemia, diabetes, dehydration, hypoglycemia, elevated liver enzymes, vitamin imbalance, electrolyte disturbances, and pediatric hyperammonemia may also occur. Patients with impaired liver or kidney function may experience increased blood urea nitrogen levels, and those with severe liver dysfunction may present with serious symptoms such as coma or loss of consciousness. When administered in large doses or in conjunction with other medications containing electrolytes, careful attention to electrolyte balance is essential. In cases of overdose, metabolic alkalosis may occur, so preparations containing sodium acetate ions should be used cautiously. Patients with a history of kidney disease, lung disease, or severe heart disease must adjust the dosage to prevent side effects due to fluid overload. Diabetic patients should frequently monitor their blood glucose levels during this medication administration. The protein-sparing effect of this medication may decrease when used with tetracycline antibiotics. For pregnant women, safety has not been established, and it should only be used when the therapeutic benefits outweigh the risks. Children may have immature liver function, so the dosing concentration should be kept low, and blood ammonia levels should be frequently monitored. Elderly patients, having decreased physical function, should be careful with slower administration speed and reduced dosage. This medication contains electrolytes, so care must be taken with electrolyte balance during large doses, and intravenous infusion should be administered slowly. Rapid infusion may cause chills or vomiting and can increase amino acid loss through the kidneys. The solution should be warmed to body temperature before use, and it should be prepared and managed in a sterile manner to reduce the risk of infection. Before use, ensure that the solution is clear and do not use if it is discolored or leaking. For storage, keep it in a sealed container to prevent exposure to air, and store in a cool room away from direct sunlight. To maintain the medication's effectiveness, keep the container tightly closed and avoid extremely hot or cold storage.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash, blisters, skin peeling, pain in mucous membranes of mouth/eyes, severe skin adverse reactions, difficulty breathing or shortness of breath, asthma attack, abnormal breathing with cough+fever, yellowing of the skin or eyes (jaundice), profound lethargy, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness,

Mild side effects

• Rash
• nausea
• vomiting
• chest discomfort
• palpitations
• rapid heartbeat (tachycardia)
• elevated blood pressure
• metabolic acidosis
• hypophosphatemia
• alkalosis

This medication should be stored in a sealed container to prevent exposure to air and kept in a cool place away from direct sunlight. To maintain the medication's effectiveness, it is important to keep the container tightly closed and to avoid excessively hot or cold conditions.

Appearance

A transparent liquid that is colorless to pale yellow in a colorless transparent glass container or a polypropylene aqueous injection container with a rubber stopper for infusion.

Package unit

200 mL/bottle, 250 mL/bottle