Brupefen Tablets 400 Milligrams (Ibuprofen)

Key information summary

Efficacy & effects

This medication is effective for rheumatoid arthritis, osteoarthritis, fever and pain caused by cold symptoms, back pain, dysmenorrhea, and relief of postoperative pain. It is also used for various painful conditions such as ankylosing spondylitis, headaches, toothaches, muscle pain, neuralgia, acute gout, as well as psoriatic arthritis, soft tissue injuries, and non-articular rheumatic diseases. The suppository helps reduce fever in children due to acute upper respiratory tract infection. By alleviating pain and inflammation associated with these various diseases and symptoms, it helps improve the patient's quality of life.

Dosage

1. Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, soft tissue injuries, non-articular rheumatic diseases, acute gout, psoriatic arthritis: Take 200-600 mg orally, 3-4 times daily. A maximum daily dose of 3200 mg may be administered. 3. Mild to moderate pain, cold: Take 200-400 mg orally, 3-4 times daily. Adjust according to age and symptoms as appropriate.

Precautions

This medication may increase the risk of gastrointestinal bleeding for individuals who regularly consume three or more glasses of alcohol daily, so it is essential to consult a doctor or pharmacist. Long-term use of this medication or for those at risk of cardiovascular disease may increase the likelihood of serious cardiovascular issues, such as myocardial infarction or stroke, thus caution is required. Serious adverse reactions such as gastrointestinal bleeding, ulcers, perforation may occur, especially in the elderly or those on long-term treatment, where the risk is heightened. Individuals with a history of gastrointestinal ulcers or bleeding or severe liver, kidney, or heart dysfunction should not take this medication. Persons with bronchial asthma or hypersensitivity to aspirin and other non-steroidal anti-inflammatory drugs should also avoid this medication. In late pregnancy, this medication should not be taken as it may cause early closure of the ductus arteriosus. After mid-pregnancy, it may lead to fetal renal dysfunction or oligohydramnios, requiring prenatal monitoring. Do not exceed the recommended dosage and do not take it in conjunction with other non-steroidal anti-inflammatory drugs. If breastfeeding, consider stopping breastfeeding or discontinuing the medication, as it may pass into breast milk and cause serious adverse reactions in infants. Caution is required when driving or operating machinery, as this medication may slow reaction times, particularly when taken with alcohol. Anyone with blood disorders, liver or kidney disease, heart disease, hypertension, or a history of hypersensitivity should consult a healthcare professional before taking this medication. This medication can interact with certain drugs; therefore, patients taking ACE inhibitors, lithium, diuretics, methotrexate, anticoagulants, selective serotonin reuptake inhibitors should exercise caution. If severe allergic reactions, skin rashes, breathing difficulties, bleeding, liver function abnormalities, or decreased kidney function occur during the course of treatment, discontinue use immediately and consult with healthcare professionals. Regular blood tests and liver and kidney function tests should be conducted during long-term use, and if any unusual symptoms arise, dosage should be adjusted or discontinued. This medication is a symptomatic treatment to help relieve symptoms, which is safest when taken at the minimum duration and minimum dose necessary. In case of overdose, symptoms such as dizziness, nausea, vomiting, liver function abnormalities, and renal failure may occur, necessitating an immediate visit to a medical facility. Keep this medication out of the reach of children, and store it in its original container to prevent misuse or deterioration in quality.

Side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor (serious allergic reaction), severe rash with high fever, blisters, mucosal pain in the mouth/eyes (serious skin adverse reactions), asthma attack, difficulty breathing, respiratory distress accompanied by coughing and fever, yellowing of the skin or eyes (jaundice), severe systemic malaise (liver dysfunction), sudden and very severe headache, seizures, confusion

Interactions

Do not take this medication with other non-steroidal anti-inflammatory drugs, low-dose aspirin, or high-dose methotrexate. Consult with a doctor or pharmacist if taken together with ACE inhibitors, lithium, furosemide, thiazide diuretics, coumarin anticoagulants (such as warfarin), and selective serotonin reuptake inhibitors.

Alternatives / Same-ingredient medications

• 

  Brupefen Tablets 200 Milligrams (Ibuprofen)

  Same ingredient
• 

  Scopen Tablets 400 Milligrams (Ibuprofen)

  Same ingredient
• Children's Brufen Syrup (Ibuprofen)

  Same ingredient
• Carol Syrup (Ibuprofen)

  Same ingredient

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