Medication info
Anaprox Tablet (Naproxen Sodium)

Anaprox Tablet (Naproxen Sodium)

OTC medicationTablet경구
Ingredient · strength
Naproxen Sodium›275mg / 1 tablet
Manufacturer / importer
(주)종근당
Appearance
Blue oval film-coated tablet
Packaging
10 tablets (10 tablets/PTP x 1), 100 tablets/bottle, 500 tablets/bottle
Approval status
Active

MFDS item code 198300064 · Notified 1983.06.07 · Insurance code 643301620

Summary

Main use
Relief of inflammation and pain associated with rheumatoid arthritis and osteoarthritis
Who takes it
Adults
Adult dose
1. Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis: administer 275-550 mg of Naproxen Sodium orally twice a day (every 12 hours). 2. Acute gout: administer an initial dose of 825 mg orally, then 275 mg orally every 8 hours until the attack subsides. 3. Skeletal muscle disorders, postoperative pain, pain after tooth extraction, dysmenorrhea, tendinitis, bursitis: administer an initial dose of 550 mg orally.

Ingredients

Manufacturer
(주)종근당

Efficacy & effects

Relief of inflammation and pain associated with rheumatoid arthritis and osteoarthritis

  • Rheumatoid arthritis
  • osteoarthritis
  • ankylosing spondylitis
  • tendinitis
  • acute gout
  • dysmenorrhea
  • bursitis
  • skeletal muscle disorders
  • sprains
  • strains
  • trauma
  • low back pain
View approved original text

This medication is effective for inflammatory diseases of the joints and muscles such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It is also used to treat tendinitis, acute gout, and dysmenorrhea. Additionally, it helps with bursitis, muscle and ligament injuries, back pain, postoperative pain relief, as well as migraine and pain relief after tooth extraction. Overall, it is widely used for the treatment of various types of pain and inflammatory diseases.

How to take

Adult dose

1. Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis: administer 275-550 mg of Naproxen Sodium orally twice a day (every 12 hours). 2. Acute gout: administer an initial dose of 825 mg orally, then 275 mg orally every 8 hours until the attack subsides. 3. Skeletal muscle disorders, postoperative pain, pain after tooth extraction, dysmenorrhea, tendinitis, bursitis: administer an initial dose of 550 mg orally.

Precautions

Patients who regularly consume alcohol, particularly more than three drinks a day, should consult with a doctor or pharmacist before taking this medication, as taking it with alcohol may increase the risk of gastrointestinal bleeding. This medication may increase the risk of cardiovascular disease, especially serious vascular issues such as myocardial infarction or stroke. Therefore, individuals with cardiovascular conditions or risk factors should exercise extra caution. If cardiovascular symptoms occur during treatment, consult healthcare professionals immediately. This medication can also cause serious gastrointestinal issues such as bleeding, ulcers, and perforations. The risk may be higher in the elderly or those on long-term treatment, and any gastrointestinal symptoms require immediate medical attention. Individuals with specific conditions such as peptic ulcer, severe blood disorders, liver disease, heart failure, kidney disease, or hypertension should not take this medication. Additionally, those who have allergies to this medication's ingredients or have had hypersensitivity reactions to non-steroidal anti-inflammatory drugs like aspirin should avoid its use. Individuals with a history of peptic ulcers or blood disorders, liver disease, kidney disease, hypertension, or asthma should use this medication cautiously and consult a healthcare provider if unusual symptoms occur. Taking this medication can lead to various side effects including allergic reactions, gastrointestinal bleeding, blood disorders, liver or kidney function abnormalities, skin rashes, headaches, dizziness, auditory and visual disturbances. If these symptoms appear, discontinue use immediately and consult a doctor. The medication should be used at the smallest effective dose for the shortest necessary duration to minimize the risk of side effects; long-term users should undergo regular blood tests and liver and kidney function assessments. Patients with abnormalities in cardiovascular, gastrointestinal, liver, or kidney function should be closely monitored during treatment. The risk of side effects may increase when taken with other non-steroidal anti-inflammatory drugs, so co-administration is not recommended. Additionally, it may interact with some antihypertensive drugs, diuretics, anticoagulants, and chemotherapy agents, so inform your healthcare provider of any other medications you are taking. This medication should not be used during pregnancy, especially in the later stages, as it may affect fetal kidney function in the second half of pregnancy. It is also advisable to avoid use during breastfeeding, as it can pass into breast milk and cause side effects in the baby. It is preferable not to administer this medication to children under 2 years of age, as safety has not been established, and it should be administered cautiously at the minimum effective dose in children or the elderly. Overdosage may result in symptoms such as drowsiness, dyspepsia, and vomiting; seek immediate medical attention if these symptoms occur. Lastly, this medication should be stored out of reach of children, and transferring it to another container may not be good for preserving its quality.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, sweating → severe allergic reaction. High fever with severe rash, blisters, skin peeling, pain in oral/eye mucosa → severe skin reaction. Shortness of breath or difficulty breathing, asthma attacks, cough + fever with respiratory distress → respiratory issues. Yellowing of the skin or eyes (jaundice), extreme lethargy → liver issues (jaundice). Sudden and very severe headache.

Mild side effects

  • Abdominal discomfort
  • stomach pain
  • abdominal pain
  • nausea
  • vomiting
  • loss of appetite
  • dyspepsia
  • heartburn
  • diarrhea
  • constipation
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  • stomatitis
  • abdominal bloating
  • black stools
  • thirst
  • agranulocytosis
  • eosinophilia
  • leukopenia
  • thrombocytopenia
  • aplastic anemia
  • hemolytic anemia
  • thrombocytopenic dysfunction
  • elevated GOT
  • GPT levels
  • hepatitis
  • kidney disorders
  • glomerulonephritis
  • hematuria
  • hyperkalemia
  • interstitial nephritis
  • nephrotic syndrome
  • renal papillary necrosis
  • proteinuria
  • renal failure
  • none

Not everyone experiences these, and they can vary from person to person.

Interactions

Drug interactions

Do not take this medication with other non-steroidal anti-inflammatory drugs and naproxen derivatives. Consult a doctor or pharmacist when taken with hydantoin anticonvulsants, sulfonamides, sulfonylurea hypoglycemics, propranolol and other beta-blockers, ACE inhibitors, loop and thiazide diuretics, probenecid, aspirin, lithium, methotrexate, coumarin anticoagulants, zidovudine, quinolone antibiotics.

Storage

This medication should be stored in a sealed container to protect it from air and moisture. The appropriate storage temperature is between 1 to 30 degrees Celsius.

Appearance and packaging

Appearance

Blue oval film-coated tablet

Package unit

10 tablets (10 tablets/PTP x 1), 100 tablets/bottle, 500 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.