Tagamet Injection (Cimetidine)

Key information summary

Efficacy & effects

This medication is used for the treatment of conditions such as Zollinger-Ellison syndrome as well as peptic ulcers, acute stress ulcers, and upper gastrointestinal bleeding due to hemorrhagic gastritis. It is effective in helping to heal ulcers by inhibiting gastric acid secretion and preventing recurrence. It aids in reducing gastrointestinal bleeding and promotes wound recovery, thereby improving patient symptoms. This medication is very useful in the treatment of gastrointestinal disorders.

Dosage

1) Intravenous injection Administer 200 mg of cimetidine intravenously every 4 to 6 hours. Do not exceed 2 g per day. 2) Drip intravenous injection Administer 200 mg of this medication intravenously every 4 to 6 hours over 2 hours. The maximum infusion rate should not exceed 150 mg per hour or 2 mg/kg/hr. For continuous intravenous infusion, the average infusion rate is to be maintained at hourly intervals for 24 hours.

Precautions

Since this medication is provided in a glass ampoule, caution is needed as glass fragments may be introduced when opening the ampoule. Special care is required when administering to children or the elderly. This medication should not be administered to patients who have hypersensitivity reactions or allergies to its ingredients, as well as those taking specific antiarrhythmic medications. Patients with renal or hepatic dysfunction, elderly individuals, children, and patients undergoing hemodialysis may require dosage adjustments or changes in administration intervals. Symptoms of gastric cancer may be hidden, so use should only be after confirming the malignancy status. This medication may affect the blood, liver, and kidneys, so if symptoms such as fatigue, fever, bleeding, jaundice, or abnormal kidney function occur, administration should be stopped immediately and a physician consulted. If allergic reactions or skin rashes, shock symptoms, or hormonal-related abnormal symptoms such as gynecomastia, increased milk secretion, or erectile dysfunction occur, administration should also be discontinued immediately. This medication may cause gastrointestinal symptoms, headache, dizziness, mental confusion, and seizures, so if any abnormal symptoms appear, consult a physician. Additionally, irregular heartbeats or severe skin reactions have rarely been reported, so these symptoms should be monitored closely. During treatment, the disease course should be closely monitored, and blood tests or liver and kidney function tests should be conducted regularly to check for abnormalities. Particularly, elderly patients, those with chronic illnesses, and immunocompromised patients are at increased risk for infections such as pneumonia and need careful monitoring. When used with other medications, drug interactions may occur, so any medications currently being taken should be reported to healthcare professionals. Pregnant or breastfeeding women should use this medication cautiously as its safety has not been established; breastfeeding should be discontinued if necessary. In case of overdose, there is a risk of respiratory depression, so seek appropriate treatment immediately at a medical institution. During intravenous injection, rapid administration should be avoided, and it should be administered slowly to reduce the risk of side effects. Store out of reach of children, and do not transfer to other containers for safety; attention should be paid to quality maintenance during storage.

Side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, cough with fever accompanied by respiratory abnormalities, yellowing of skin or eyes (jaundice), generalized extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, vision abnormalities, paralysis, urination

Alternatives / Same-ingredient medications

• 

  International Cimetidine Tablet

  Same ingredient
• 

  Cignatin Tablet (Cimetidine)

  Same ingredient
• 

  Cimetidine Tablet (Cimetidine)

  Same ingredient
• 

  Cimetidine 300mg Tablets (Cimetidine)

  Same ingredient

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