
Key information summary
Efficacy & effects
This medication is used to improve depression and depressive states. It is also effective in treating enuresis.
Dosage
As amitriptyline hydrochloride, administer 30-75 mg per day divided into 2-3 oral doses, gradually increasing to 150 mg as needed. Rarely, it may be increased to 300 mg per day. For enuresis, administer 10-30 mg before bedtime. Adjust as appropriate based on age and symptoms.
Precautions
This drug is an antidepressant used to treat psychiatric disorders such as depression. This medication can particularly increase the risk of suicidal thoughts or behavior in young people aged 18 to 24, so it should be administered with extreme caution in this age group. All patients taking this medication should be closely monitored for any suicidal tendencies or changes in behavior at the beginning of treatment and when changing doses, and family members or caregivers should also keep a careful watch on the patient's condition and consult a physician if necessary. Patients with specific conditions, such as heart disease, glaucoma, benign prostatic hyperplasia, arrhythmias, or liver dysfunction may need to avoid using this medication or use it with caution. This medication can cause drowsiness or decreased concentration, so it is advisable to avoid driving or operating hazardous machinery while taking it. In addition, this medication may interact with various drugs, so it is essential to inform the physician or pharmacist if other medications are being taken. Women who are pregnant or breastfeeding should consult thoroughly about the necessity and risks of using this medication, as it may affect the fetus or baby. The safety and efficacy of this medication have not been fully established in children and adolescents, and it is particularly not recommended for use except in patients with enuresis. Elderly patients may be more sensitive to the side effects of this medication, so treatment should start at a low dose and be monitored periodically for physical status.
Side effects
Hives, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, significantly decreased urine output, severe swelling of the body with increased blood pressure, motor paralysis, severe


