Medication info
Liriel Orally Disintegrating Tablet 75 mg (Pregabalin)

Liriel Orally Disintegrating Tablet 75 mg (Pregabalin)

Prescription medicationOrally disintegrating Tablet
Ingredient · strength
Pregabalin›75mg / 1 tablet
Manufacturer / importer
지엘파마(주)
Appearance
Light orange diamond-shaped orally disintegrating tablet
Packaging
30 tablets/PTP [10 tablets/PTP x 3], 100 tablets/PTP [10 tablets/PTP x 10]
Approval status
Active

MFDS item code 202600402 · Approved 2026.02.12

Summary

Main use
Treatment of peripheral and central neuropathic pain, adjunctive treatment for partial seizures in epilepsy, improvement of fibromyalgia
Who uses it
Adults · Children
Adult dosage
This medication is administered orally in two divided doses per day, irrespective of meals, placing it on the tongue and swallowing it without water. 1. Neuropathic Pain - Peripheral Neuropathic Pain: Start with a dose of 150 mg per day and can be increased to 300 mg per day within 3 to 7 days, with increments of up to a maximum of 600 mg per day at intervals of 7 days as needed. - Central Nervous System pain...
Children's dosage
There is insufficient safety and efficacy data for children under 12 years of age and adolescents between 12-17 years, so administration is not recommended.

Ingredients

Manufacturer
지엘파마(주)

Efficacy & effects

Treatment of peripheral and central neuropathic pain, adjunctive treatment for partial seizures in epilepsy, improvement of fibromyalgia

  • Peripheral neuropathic pain
  • central neuropathic pain
  • partial seizures
  • fibromyalgia
View approved original text

This medication is used for the treatment of peripheral and central neuropathic pain in adults. It is also used as an adjunct for the treatment of partial seizures in adults with epilepsy. Additionally, it is effective in treating fibromyalgia. In summary, this drug is used for the treatment of neuropathic pain, partial seizures in epilepsy, and fibromyalgia.

Dosage and Administration

Adult dosage

This medication is administered orally in two divided doses per day, irrespective of meals, placing it on the tongue and swallowing it without water. 1. Neuropathic Pain - Peripheral Neuropathic Pain: Start with a dose of 150 mg per day and can be increased to 300 mg per day within 3 to 7 days, with increments of up to a maximum of 600 mg per day at intervals of 7 days as needed. - Central Nervous System pain...

Children's dosage

There is insufficient safety and efficacy data for children under 12 years of age and adolescents between 12-17 years, so administration is not recommended.

Precautions

This medication may increase the risk of suicidal thoughts or behavior, so if there are abnormal changes in mood or behavior while taking it, you should immediately inform your healthcare provider. Patients with hypersensitivity to this medication should not take it. Diabetic patients may experience weight gain when taking this medication, so adjustments to their blood sugar control medications may be necessary. If allergic reactions such as angioedema occur, use should be immediately discontinued. Elderly patients should be cautious, as dizziness and drowsiness may occur when taking this medication; should such symptoms arise, there is a risk of falls and other accidents. While taking this medication, visual disturbances or changes in vision may occur, and these symptoms may improve upon discontinuation of the drug. Abruptly stopping this medication may lead to withdrawal symptoms such as insomnia, headache, and anxiety, so dosage adjustments should be made in consultation with a healthcare professional. Patients with a history of substance abuse may be at higher risk for misuse of this medication, and caution should be exercised while taking it. Patients with decreased kidney function may need dosage adjustments for this medication. Patients with heart disease should be cautious, as symptoms such as congestive heart failure may appear while taking this medication. The concomitant use of this medication with opioid analgesics can enhance central nervous system depression effects, leading to a risk of respiratory depression, so caution is advised. This medication can cause dizziness and drowsiness, so driving or operating hazardous machinery should be avoided until symptoms resolve. In early pregnancy, there is a risk of fetal malformation; therefore, women who are pregnant or planning to become pregnant should consult a doctor before taking this medication and should use effective contraception. Breastfeeding women are recommended to stop breastfeeding, as this medication can be transferred to breast milk, and the effects on infants are not fully known. In cases of overdose, symptoms such as drowsiness, confusion, depression, and seizures may occur, and immediate medical attention should be sought for appropriate treatment. Keep out of reach of children, and transferring to other containers may pose risks of accidents or degradation of quality. If severe skin rashes, swelling, or difficulty breathing occur during use of this medication, discontinue use immediately and consult a healthcare provider.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in oral or ocular mucosa, shortness of breath or difficulty breathing, asthma attack, cough with breathing abnormalities and fever, yellowing of skin or eyes (jaundice), severe generalized fatigue, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis,

Mild side effects

  • Dizziness
  • drowsiness
  • increased appetite
  • loss of appetite
  • hypoglycemia
  • confusion
  • spatial disorientation
  • irritability
  • depression
  • euphoria
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  • decreased libido
  • insomnia
  • depersonalization
  • sexual hyperesthesia
  • restlessness
  • anxiety
  • mood swings
  • emotional flattening
  • emotional elevation
  • difficulty finding appropriate terms
  • hallucinations
  • abnormal dreams
  • increased libido
  • panic attacks
  • impulsivity
  • apathy
  • ataxia
  • motor coordination disorders
  • equilibrium disturbances
  • memory loss
  • attention deficit
  • memory impairment
  • tremors

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from air and moisture. It is best to maintain storage temperature between 1 to 30 degrees Celsius (room temperature).

Appearance and packaging

Appearance

Light orange diamond-shaped orally disintegrating tablet

Package unit

30 tablets/PTP [10 tablets/PTP x 3], 100 tablets/PTP [10 tablets/PTP x 10]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.