Bonprazan Tablets 20 mg (Bonprazan Fumarate)

Adult dose

● Treatment of gastric ulcers Adults: Administer vonoprazan 20 mg orally once daily. Treatment is usually continued for up to 8 weeks. ● Treatment of erosive gastroesophageal reflux disease and maintenance therapy after treatment Treatment: Adults: Administer vonoprazan 20 mg orally once daily. Treatment is usually continued for up to 4 weeks. If the effect is insufficient, treatment may be continued for up to 8 weeks. Maintenance therapy: Administer 10 mg orally once daily. If the effect is insufficient, 20 mg may be administered orally once daily. ● Prevention of recurrence of gastric or duodenal ulcers during administration of nonsteroidal anti-inflammatory drugs (NSAIDs) Adults: Administer vonoprazan 10 mg orally once daily.

This medication should not be used in patients with hypersensitivity or allergy to the components of this medication. It is also contraindicated in patients taking certain antiviral medications. Patients with impaired kidney function and those with liver dysfunction should use this drug with caution. Elderly patients also require care due to possible deterioration of bodily functions. This medication can cause various gastrointestinal-related side effects such as abdominal pain, constipation, diarrhea, nausea, and vomiting. Serious side effects, such as allergic reactions, skin rashes, liver dysfunction, and blood abnormalities may also occur rarely. If symptoms arise, immediate consultation with healthcare professionals is necessary. If liver dysfunction is suspected, it is crucial to stop using this medication immediately, and regular tests, such as endoscopic examinations, are needed for long-term use. Patients with a history of gastric or duodenal ulcers should be especially cautious, as it may hide the symptoms of gastric cancer; therefore, the malignancy status should be confirmed before administration. Long-term high-dose use may increase the risk of osteoporosis-related fractures, so patients at high risk for fractures should take this medication more carefully. This medicine increases gastric acidity, which may hinder the absorption of some drugs, so it is essential to consult a physician because the effect may decrease when used with certain medications. Women who are pregnant or may become pregnant should preferably avoid using this medication, and breastfeeding women are advised to avoid nursing while taking this medication. The safety in children has not been established, so it is preferable not to use this medication in pediatric patients. Additionally, when taking the medication, care must be taken to avoid swallowing the wrapped tablet sheet, as it could damage the esophagus and cause serious complications.

Upper abdominal pain, constipation, dental caries, diarrhea, gastric polyps, gastritis, nausea, stomatitis, vomiting, peripheral edema, seasonal allergies, bronchitis, gastroenteritis, influenza, nasopharyngitis, esophageal candidiasis, periodontitis, pharyngitis, sinusitis, contusion, fall, ligament sprain, procedure-related bleeding, increased alanine aminotransferase, increased creatine phosphokinase in the blood, increased triglycerides in the blood, increased uric acid in the blood, increased γ-glutamyltransferase, arthralgia, low back pain, osteoarthritis, periarthritis, dizziness, insomnia, allergic rhinitis, upper respiratory tract inflammation, contact dermatitis, eczema, anemia, iron deficiency anemia, aortic valve dysfunction, atrial fibrillation, right bundle branch block, vertigo, subacute thyroiditis, corneal detachment, dry eyes, eyelid eczema, open-angle glaucoma, abdominal discomfort, abdominal distension, lower abdominal pain, abdominal pain, irregular bowel movements, appendicitis, cheilitis, duodenal polyps, small bowel colitis, discomfort in the upper abdomen, stool discoloration, bloating, functional gastrointestinal disorder, gastric bleeding, gastric mucosal lesions, erosive gastritis, hemorrhagic gastritis, abnormal gastric sounds, gastroesophageal reflux disease, glossitis, hemorrhoids, oral sensory loss, intestinal obstruction, colorectal polyps, labial erosion, salivary gland pain, chest pain, facial edema, disease sensation, edema, polyp, fever, thirst, drug-induced liver injury, abnormal liver function, otitis media, pneumonia, subcutaneous abscess, facial tinea, muscle injury, increased aspartate aminotransferase, increased eosinophil count, increased alkaline phosphatase in the blood, increased bilirubin in the blood, increased cholesterol in the blood, decreased iron in the blood, increased iron in the blood, increased blood lactate dehydrogenase, increased magnesium in the blood, increased potassium in the blood, increased urea in the blood, presence of hematuria, increased eosinophil count, presence of glucosuria, increased liver enzymes, abnormal liver function tests, decreased lymphocyte count, decreased neutrophil count, increased neutrophil count, presence of proteinuria, abnormal kidney function tests, increased vitamin B12, decreased white blood cell count, increased white blood cell count, diabetes mellitus, gout, hypertriglyceridemia, hyperuricemia, type 2 diabetes mellitus, muscle weakness, cervical pain, polyarthritis, rotator cuff syndrome, bladder cancer, gastric adenoma, malignant fibrous histiocytoma, malignant neoplasm of the renal pelvis, headache, sensory loss, peripheral neuropathy, cochlear nucleus hemorrhage, drowsiness, ureteral stones, frequent urination, asthma, laryngeal pain, oropharyngeal discomfort, vascular edema, dermatitis, erythema, petechiae, pruritic rash, pruritus, generalized rash, rash, urticaria, blue toe syndrome, hypertension, drug hypersensitivity, urticaria, drug rash, pancytopenia, agranulocytosis, leukopenia, thrombocytopenia, hepatotoxicity, jaundice, rash, polymorphic erythema, Stevens-Johnson syndrome, toxic epidermal necrolysis

This medication should be stored in a tightly sealed container to prevent exposure to air, and it is best kept at room temperature between 1 and 30 degrees Celsius. Storing it this way can help maintain the effectiveness of the medicine for a longer period.

Appearance

Pale red oval film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP)×3]