Empagazmet Tablet 12.5/1000 Milligrams (Empagliflozin 2L-Proline, Metformin)

Adult dose

The recommended dosage for this medication is 1 tablet per dose, twice a day. For patients who cannot achieve sufficient blood sugar control with metformin alone or in combination with other medications such as insulin, take 5 mg of empagliflozin twice a day (total daily amount 10 mg) along with the existing dosage of metformin. If tolerance to 10 mg of empagliflozin (total daily amount) is good but additional blood sugar control is needed, the dose may be increased to 25 mg of empagliflozin.

This medication can cause severe lactic acidosis, so if symptoms related to lactic acidosis occur, discontinue use immediately and seek medical attention. Caution is advised when used in conjunction with other diabetes medications due to the risk of hypoglycemia. Patients with moderate to severe renal impairment or acute kidney problems should not take this medication. In situations that may affect renal function such as acute infections, heart problems, pre- and post-surgery, or dehydration, the use of this medication should be avoided or temporarily discontinued. Pregnant or breastfeeding women should not use this medication, and it is not recommended for children under 18 years of age. This medication may increase the risk of urinary tract infections and genital infections, so quick treatment is necessary if infection symptoms arise. Patients at risk of fluid loss or dehydration should use this medication with caution, particularly elderly patients, who should be closely monitored for hydration status. Regular monitoring is needed as liver function abnormalities or heart function decline may occur during treatment with this medication. There is a risk of hypoglycemia, therefore dose adjustments may be necessary when used with insulin or sulfonylureas. Vitamin B12 deficiency may occur, and it is advisable to check blood Vitamin B12 levels during prolonged use. Alcohol consumption can increase the risk of lactic acidosis, so excessive drinking should be avoided while using this medication. This medication may interact with other drugs; therefore, individuals taking other medications should consult with a physician or pharmacist. In the case of overdose, seek medical care immediately, and blood dialysis may be required. Keep out of reach of children, and store in the original container to maintain quality. Immediately inform healthcare professionals if any unusual symptoms such as fever, pain, or swelling occur around the perineum during treatment with this medication.

Serious side effects

Urticaria, angioedema, necrotizing fasciitis of the perineum, urosepticemia, pyelonephritis, lactic acidosis, ketoacidosis, acute kidney injury, cerebral infarction, myocardial infarction, hepatitis, acute cholecystitis, autoimmune hepatitis, cholelithiasis, liver abnormalities (yellowing of skin or eyes), severe allergic reactions (hives, severe swelling, chest tightness, difficulty breathing, sweating, pallor), severe skin reactions (severe rash with high fever,

Mild side effects

• Hypoglycemia
• urinary tract infection
• genital infection
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. Also, avoid extremely hot or cold places, and storing at room temperature between 1 to 30 degrees Celsius is recommended.

Appearance

Dark purple oval film-coated tablet

Package unit

30 tablets/bottle, 60 tablets/bottle