Niserkode Tablet 10 mg (Nisergoline)

Adult dose

* 5 mg, 10 mg Adults: Administer 5 ∼ 10 mg of nicergoline orally 3 times daily before meals. Adjust the dose as appropriate according to symptoms. * 30 mg Adults: Administer 30 mg of nicergoline orally once daily before a meal. If the desired effect is not achieved at this dose, it may be increased to 60 mg. The dose may be reduced after symptoms improve. For patients with impaired renal function (serum creatinine >175 µmol/L) (2 mg/dL), administer a reduced dose.

This medication should not be used in certain patients. Patients who are allergic to this drug or ergot alkaloids should not take it. Patients with acute heart problems or acute bleeding should also avoid using this drug. Patients taking sympathomimetic agents should not take this drug together. Patients with a very slow heart rate should also avoid taking this drug. Patients who have not completed hemostasis after a cerebral hemorrhage or those with orthostatic hypotension should avoid this drug. Patients with mild bradycardia or impaired renal function should use this drug with caution. This medication may rarely cause symptoms such as indigestion, diarrhea, constipation, nausea, vomiting, abdominal pain, or dry mouth. Liver function test values may increase. Cardiovascular symptoms such as dizziness, orthostatic hypotension, blood pressure changes, and increased blood uric acid levels may rarely occur. Neurological symptoms such as drowsiness, fatigue, headache, and insomnia may also occur. Rarely, hypersensitivity reactions such as skin rash, itching, or fever may occur. Taking this drug with other antihypertensive agents may enhance the blood pressure-lowering effect, so blood pressure should be checked frequently. It may affect uric acid metabolism, so patients with a history of gout should use it with caution. Caution is needed when driving or operating machinery after taking this medication. This drug is metabolized by specific enzymes in the liver, so there may be interactions with other medications related to these enzymes. Pregnant women or women who may become pregnant should consult a doctor before taking this drug, as there have been reported harmful effects on the fetus in animal studies, requiring careful judgment. Nursing mothers should avoid using this drug or discontinue breastfeeding, as it may be secreted in breast milk. The elderly should be careful about dosage adjustments due to potentially diminished body functions. It is best to avoid using this drug in children as its safety has not been established. In case of overdose, blood pressure may temporarily decrease, so blood pressure should be monitored frequently, and necessary measures should be taken. This drug should be kept out of the reach of children and stored in its original container, tightly closed to prevent contamination or improper use.

• Loss of appetite
• diarrhea
• constipation
• nausea
• vomiting
• intermittent upper abdominal pain
• cramps
• thirst
• elevated ALT
• elevated AST

This drug may be sensitive to air or moisture, so it must be stored in a tightly sealed container. It is best to maintain the storage temperature between 1 to 30 degrees Celsius at room temperature. This will help preserve the medication's efficacy for a long time.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle