Bukwang Brivaracetam 100 mg Tablet

Adult dose

This medicine is taken twice daily. The recommended initial dose is 25mg or 50mg per dose, based on the healthcare professional's assessment of potential adverse effects relative to seizure reduction. Based on clinical response and tolerability, the dose may be increased or decreased from 50mg per day [25mg per dose, twice daily] to 200mg per day [100mg per dose, twice daily]. Swallow this film-coated tablet whole with water. It may be taken with or without food. If you miss one or more doses, take one dose as soon as you remember, and then take the next dose at the next scheduled morning or evening time. If you wish to stop taking this medicine, gradually reduce the dose by 50mg per day at 1-week intervals. After taking 50mg per day for 1 week, a dose of 20mg per day is recommended for the final week (see section 2. Warnings). Older adults (65 years and older): No dosage adjustment is required in older adults. Clinical experience in patients aged 65 years or older is limited. Renal impairment: No dosage adjustment is required in patients with renal impairment. This medicine is not recommended for patients with end-stage renal impairment who are receiving hemodialysis. Hepatic impairment: Exposure to this medicine is increased in patients with hepatic impairment. The recommended initial dose for patients with hepatic impairment is 50mg per day [25mg per dose, twice daily], and the recommended maximum dose is 150mg per day [75mg per dose, twice daily].

This medication is used for the treatment of epilepsy and may increase the risk of suicidal thoughts or suicidal behaviors, therefore patients and caregivers should carefully monitor for these symptoms. Central nervous system symptoms such as drowsiness, fatigue, and dizziness may occur during the early part of treatment and can occur at any point during therapy. Abrupt discontinuation of the medication may lead to more frequent seizures; therefore, it is safer to gradually reduce the dose before stopping. This medication should not be taken by individuals with a history of allergic reactions to it or genetic conditions such as lactose intolerance. Patients with impaired liver function may require dose adjustment and should take the medication as directed by their physician. If a rash or severe skin reaction occurs while taking this medication, it should be discontinued immediately and medical consultation should be sought. Drug interactions may occur when taken with other antiepileptic medications, certain antibiotics, antifungals, etc.; therefore, patients must inform their healthcare providers about all other medications they are taking. The effects of this medication on the fetus during pregnancy are unclear, so it should be administered only under medical judgment when absolutely necessary. Since this medication may be secreted in breast milk, whether to continue breastfeeding should be discussed with a physician. Safety and efficacy in children under 16 years have not been established, so it should be given to pediatric patients with caution. This medication may cause drowsiness or dizziness, therefore it is advisable to avoid driving or operating machinery during the initial phase of treatment. In case of overdose, there is no specific antidote, and if suspected, appropriate medical treatment should be sought immediately.

• suicidal ideation
• suicidal behavior
• drowsiness
• fatigue
• dizziness
• akathisia
• influenza
• type 1 hypersensitivity reaction
• neutropenia
• decreased appetite

The medication should be stored in a tightly closed container to prevent exposure to air or moisture, and it is recommended to store it at room temperature, between 1°C and 30°C. Proper storage will help maintain the medication's effectiveness and prevent degradation.

Appearance

Greenish oval film-coated tablet

Package unit

30 tablets/bottle, 120 tablets/bottle