Brivaracetam 100 mg Tablets

Adult dose

This medicine is taken twice daily. The recommended initial dose is 25mg or 50mg per dose, based on the healthcare professional's assessment of potential adverse effects relative to seizure reduction. Based on clinical response and tolerability, the dose may be increased or decreased from 50mg per day [25mg per dose, twice daily] to 200mg per day [100mg per dose, twice daily]. Take this film-coated tablet whole with water, with or without food. If you miss a dose If you miss one or more doses, take one dose as soon as you remember, and then take the next dose at the next morning or evening dosing time. Discontinuation If you wish to discontinue this medicine, gradually reduce the dose by 50mg per day at 1-week intervals. After taking 50mg per day for 1 week, a dose of 20mg per day is recommended during the final week (see section '1. Warnings'). Elderly patients (65 years and older) No dose adjustment is necessary in elderly patients. Clinical experience in elderly patients aged 65 years and older is limited. Renal impairment No dose adjustment is necessary in patients with renal impairment. This medicine is not recommended for patients with end-stage renal disease receiving hemodialysis. Hepatic impairment Exposure to this medicine is increased in patients with hepatic impairment. The recommended initial dose for patients with hepatic impairment is 50mg per day [25mg per dose, twice daily], and the recommended maximum dose is 150mg per day [75mg per dose, twice daily].

This medication is used for the treatment of epilepsy and may cause mental health issues such as suicidal thoughts or behavior, so the patient's mental state should be closely monitored during treatment. Additionally, central nervous system symptoms such as drowsiness, fatigue, and dizziness may occur, so caution is required when driving or operating machinery. Abruptly discontinuing this medication can worsen seizures; therefore, it should only be stopped gradually according to a doctor's instructions. Do not take this medication if you have an allergy to the active ingredient or any components in the medication, and patients with certain genetic disorders such as lactose intolerance should also avoid this medication. Patients with poor liver function may need to adjust the dosage of this medication and should consult a physician. If severe skin rashes or allergic reactions occur, discontinue use immediately and inform medical staff. This medication may have drug interactions when taken with other antiepileptic drugs; therefore, it is essential to inform your doctor or pharmacist of all medications currently being taken. Avoid alcohol consumption while taking this medication, as it may further impair psychomotor function. Women who are pregnant or planning to become pregnant should consult a doctor before taking this medication, and nursing mothers should exercise caution as the medication may pass into breast milk. It is advised not to use this medication in children under 16, as its safety and efficacy have not been established. In case of overdose, symptoms such as drowsiness, dizziness, anxiety, and depression may appear, and since there is no specific antidote, appropriate medical treatment should be sought immediately.

• suicidal thoughts
• suicidal behavior
• drowsiness
• fatigue
• dizziness
• coordination disorders
• influenza
• type I hypersensitivity reaction
• neutropenia
• loss of appetite

Store this medication in a tightly closed container to protect it from air and moisture. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

Pale greenish oval film-coated tablet

Package unit

56 tablets/box [(14 tablets/PTP * 4)]