Traduo M-Pass Extended Release Tablet 25/5/1000 mg (Empagliflozin, Linagliptin, Metformin)

Adult dose

The dosage of this medication is determined based on each ingredient's maximum daily dose of empagliflozin 25mg, linagliptin 5mg, and extended release metformin hydrochloride 2000mg, considering the patient's current treatment regimen, efficacy, and tolerance. This medication is taken once daily in the evening with meals to reduce gastrointestinal adverse effects associated with metformin hydrochloride, and dosage adjustments for metformin hydrochloride should be made as needed.

This medication can rarely cause a serious metabolic complication called lactic acidosis, which has been associated with reported cases of death. Therefore, it should not be used in patients with severely impaired kidney function, acute or chronic metabolic acidosis, or those undergoing dialysis. Additionally, it should be avoided in patients with severe heart failure or unstable physical conditions such as acute myocardial infarction, shock, or severe infections. Medication should be temporarily stopped before and after examinations using radiologic iodine contrast agents due to the risk of kidney damage and lactic acidosis. The level of the drug in the blood may vary depending on kidney function, so periodic kidney function tests are required before and during treatment. Special attention is needed for elderly patients or those with impaired kidney function. Careful monitoring is also required for patients with heart failure or a history of pancreatitis; if symptoms of acute pancreatitis occur, medication should be discontinued immediately. This medication may cause hypoglycemia, so dosage adjustments may be necessary to reduce the risk of hypoglycemia when used in conjunction with drugs that induce hypoglycemia, such as insulin or sulfonylureas. Irregular meals, vigorous exercise, and excessive alcohol intake may also increase the risk of hypoglycemia or lactic acidosis. Various side effects such as urinary tract infections, genital fungal infections, increased urination, decreased fluid volume, and abnormal liver function may occur during treatment with this medication; patients should consult their healthcare provider if unusual symptoms arise. Especially, if pain or swelling occurs around the perineum, immediate medical attention should be sought. The risk of lactic acidosis may increase when taken with alcohol, so excessive drinking should be avoided during treatment. Additionally, there may be interactions with other medications, so it is essential to inform healthcare providers of any other medications being taken. Finally, tablets should be swallowed whole without chewing or crushing, and while the drug shell may appear in stool, this is a normal occurrence.

Serious side effects

• Hives
• angioedema
• severe swelling (edema)
• chest tightness
• difficulty breathing
• cold sweats
• pallor
• severe rash with fever
• blisters
• skin peeling

Mild side effects

• Urinary tract infections
• vulvovaginitis
• balanitis and other genital infections
• nasopharyngitis
• headache
• cough
• constipation
• oral ulcers
• itching
• rash

This medication should be stored in a tightly closed container to protect it from exposure to air or moisture. Additionally, it is recommended to store the medication at room temperature between 1°C and 30°C, avoiding extremely cold or hot places.

Appearance

Pink oval film-coated extended release tablet

Package unit

30 tablets/bottle