Yuhan MMET Sustained Release Tablet 25/1000 mg (Empagliflozin, Metformin)

Adult dose

The dosage of this medication will be determined based on each patient's current treatment regimen, efficacy, and tolerability, while not exceeding Empagliflozin 25 mg and sustained-release Metformin Hydrochloride 2000 mg. This medication is taken once daily in the evening with food. The increment of Metformin Hydrochloride dosage should be done gradually. The initial recommended dosage is Empagliflozin 10 mg and the patient's existing Metformin dose, provided it is well tolerated.

This medication is used for the treatment of diabetes and contains two components, Empagliflozin and Metformin. There are several important precautions to consider when taking this medication. Firstly, due to the Metformin component, there is a rare risk of severe side effect known as lactic acidosis, which occurs when excess lactic acid builds up in the body, leading to a dangerous condition. Lactic acidosis can be life-threatening, so if symptoms appear, immediate medical attention is necessary. Moreover, caution is required when taken with other diabetes medications like insulin or sulfonylureas, as this can lead to severe hypoglycemia. This medication should not be used in patients with severely impaired kidney function, acute infections, dehydration, severe heart issues, or type 1 diabetes. Additionally, it should be discontinued prior to examinations using contrast agents and not resumed until kidney function is confirmed to be normal post-examination. Pregnant women or those who may become pregnant, individuals with poor liver function, and those who consume excessive alcohol should also avoid this medication. This medication may increase urine output, so individuals at risk of dehydration should closely monitor their fluid status, and elderly patients or those with decreased kidney function should use this with extra caution. During use, urinary tract infections or genital infections may occur, and if related symptoms appear, immediate consultation with a physician is necessary. Furthermore, Metformin can reduce vitamin B12 levels, so it is advisable to monitor vitamin B12 status during prolonged use. This medication should be swallowed whole; do not chew or crush it, and it is normal for the tablet shell to appear in the stool. Lastly, if there are abrupt changes in body condition or unusual symptoms during the course of taking this medication, it is essential to consult healthcare professionals, and regular monitoring of kidney function and blood glucose levels is important.

Serious side effects

Hives, severe swelling (edema), angioedema, chest tightness, difficulty breathing, lactic acidosis, ketoacidosis, urosepsis, pyelonephritis, perineal necrosis, acute kidney injury, liver abnormalities (abnormal liver function tests, hepatitis), myocardial infarction, cerebral infarction, concussion, headache, confusion, visual disturbances, paralysis, severe edema accompanied by elevated blood pressure, hypoglycemia (including severe hypoglycemia), sepsis, shock, acute myocardial infarction

Mild side effects

• Hypoglycemia
• urinary tract infection
• genital infection
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. The storage temperature should be maintained at room temperature between 1 and 30 degrees Celsius. This will help preserve the efficacy of the medication over time.

Appearance

Pink oval film-coated sustained release tablet

Package unit

30 tablets/bottle