Polmin M-Extended Release Tablets 12.5/1000 mg (Empagliflozin, Metformin)

Adult dose

This medication is taken once daily in the evening with meals. The 10/1000 mg extended-release tablet or the 25/1000 mg extended-release tablet is taken once daily, one tablet at a time. Patients taking the 5/1000 mg extended-release tablet or the 12.5/1000 mg extended-release tablet should take two tablets at once, once daily. To maintain the extended-release properties, do not split, crush, grind, or chew the tablet; swallow it whole. In the beginning,

This medication contains two components for treating diabetes. Caution is required since rare side effects, such as severe lactic acidosis, may occur while taking this medication. Lactic acidosis is a serious condition resulting from an excessive buildup of lactic acid in the body and can sometimes be life-threatening. Moreover, the risk of hypoglycemia may increase when this medication is taken in conjunction with insulin or sulfonylureas, so blood sugar levels should be closely monitored. Patients with significantly impaired kidney function or certain severe illnesses should not take this medication. As this medication can affect kidney function, regular kidney function tests should be conducted before and during treatment. In special circumstances, such as dehydration, severe infections, unstable heart function, or before and after surgeries, temporarily discontinuing the medication may be necessary. There may be an increased risk of genital and urinary tract infections, so if symptoms of infection occur, immediate consultation with a healthcare provider is advised. Additionally, vitamin B12 deficiency may occur, thus checking through blood tests during long-term use is recommended. It is safest for pregnant women, women who may become pregnant, and breastfeeding women to avoid this medication. Caution is also advised for elderly patients, those with poor nutritional status, and those who consume alcohol excessively. This medication may interact with other drugs, so it is essential to inform healthcare providers of any other medications being taken, especially when taken with drugs that may affect kidney function. Tablets should be swallowed whole, and while the coating may be excreted in stool, this is normal. If abnormal symptoms occur, consult a doctor immediately and regular check-ups are necessary to ensure safe medication use.

Serious side effects

Urticaria, angioedema, perineal necrosis, ketoacidosis, lactic acidosis, cerebral infarction, myocardial infarction, acute cholecystitis, autoimmune hepatitis, cholelithiasis, hepatitis, pneumonia, sepsis, acute kidney injury, acute pyelonephritis, severe edema accompanied by elevated blood pressure, vascular stent thrombosis, deep vein thrombosis, diabetic ketoacidosis, acute myocardial infarction, shock, hypoxia, lactic acidosis due to cardiopulmonary disease, and severe allergic reactions (severe swelling

Mild side effects

• Hypoglycemia
• genital mycotic infections
• vulvitis
• balanitis and other genital infections
• urinary tract infections
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. It is important to maintain storage temperatures between 1 degrees and 30 degrees Celsius to preserve the medication's efficacy and safety.

Appearance

Brown, biconvex, oval-shaped extended-release film-coated tablet

Package unit

30 tablets/bottle