Anzenojeong (Drosperinone, Estradiol)

Adult dosage

This medication should be taken orally as one tablet per day without interruption. Women who have not been on hormone replacement therapy or those switching from other continuous combination preparations can start taking this medication at any time. Women receiving cyclic or sequential combination hormone replacement therapy should commence this medication the day after completing their previous treatment. Each pack allows for a 28-day course of treatment.

Children's dosage

This medication is not used in children and adolescents.

This medication requires caution for cardiovascular health. It should not be used for the prevention of coronary heart disease, as it may increase the risk of cardiovascular disease, breast cancer, and thrombosis. The treatment duration should be kept as short as possible, and regular evaluations by a physician are required. Patients at high risk for thrombosis should be monitored particularly closely. It is recommended to temporarily discontinue this medication before major surgery or during prolonged immobility. Due to the increased risk of breast cancer and endometrial cancer, annual breast examinations and self-exams, along with regular checks for endometrial status, are necessary. This medication should not be administered to individuals with undiagnosed genital bleeding, a history of breast cancer, suspected endometrial cancer, a history of thrombosis, severely impaired liver or kidney function, or to pregnant or breastfeeding women. Patients with specific conditions such as fibroids, hypertension, diabetes, liver disease, or headaches should be administered with caution, and if symptoms worsen during treatment, they should consult their physician immediately. Common side effects include breast pain, genital bleeding, and gastrointestinal pain, while rare but serious side effects such as thrombosis and breast cancer can occur. Patients should inform healthcare providers immediately if any unusual symptoms arise. This medication may interact with other drugs, so patients should inform their doctor or pharmacist of any medications they are taking, and it is advisable for patients with liver dysfunction to avoid taking it. Use during pregnancy is strictly prohibited, and if pregnancy is confirmed, the medication should be discontinued immediately. It is also not recommended to use during breastfeeding. Regular health check-ups and blood tests should be conducted to monitor for any abnormalities before and during treatment, and the dosage and duration prescribed by the physician should be strictly adhered to.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in oral or ocular mucous membranes, shortness of breath or respiratory difficulty, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and very severe headaches, thunderclap headache, seizures, confusion, visual disturbances, paralysis.

Mild side effects

• Breast pain
• female genital bleeding
• gastrointestinal and abdominal pain
• irregular bleeding
• weakness
• localized swelling
• generalized swelling
• fatigue
• abnormal laboratory test results
• increased sweating

This medication should be stored in a tightly sealed container to protect it from air and moisture, and it is best kept at room temperature between 1 and 30 degrees Celsius.

Appearance

Red round film-coated tablet

Package unit

28 tablets/box [(28 tablets/PTP*1)]