Shusta Tablet 2.5mg (Rosuvastatin Calcium)

Adult dosage

This drug may be taken at any time of day regardless of meals. The initial dose is 2.5 or 5 milligrams once daily, and if a greater reduction in LDL cholesterol is required, maintenance dosing can be adjusted accordingly. The maintenance dose is 10 milligrams once daily, which is where most patients are adjusted. The maintenance dose should be appropriately adjusted based on LDL cholesterol levels, treatment goals, and patient responses at intervals of 4 weeks or more, and can be increased up to a maximum of 20 milligrams per day. Elderly: Dose adjustment is not necessary. Renal impairment patients: For mild and moderate renal impairment, dose adjustment is not required. This drug must not be administered to patients with severe renal impairment. Caution should be exercised for patients with moderate renal impairment when administering this drug at 20mg. Hepatic impairment patients: There was no increase in systemic exposure to rosuvastatin in patients with Child-Pugh scores of 7 or less, but there was an increase in those with Child-Pugh scores of 8 or 9. Renal function testing should be considered for these patients. There is no experience in administering this drug to patients with Child-Pugh scores exceeding 9. This medication should not be administered to patients with active liver disease. Ethnicity: Systemic exposure to this drug increases in Asian patients, thus the recommended initial dose is 2.5 or 5 milligrams. Dosing at 40 milligrams is contraindicated. Patients susceptible to myopathy: The recommended initial dose for patients prone to myopathy is 2.5 or 5 milligrams. In some of these patients, dosing at 40 milligrams is contraindicated.

This drug should not be administered to certain patients. First, patients with an allergy to any ingredient of this drug or active liver disease should not take it. Additionally, patients with muscle disorders or those taking certain immunosuppressants, and those with severe renal impairment should not use this medication. Pregnant or nursing women, as well as women of childbearing age not using appropriate contraception, should avoid this drug, and it is only to be administered to women of childbearing age if they are highly unlikely to be pregnant and fully aware of the associated risks to the fetus. Patients at high risk for muscle-related side effects, such as those with moderate renal impairment, hypothyroidism, a history of genetic muscle disorders, alcohol dependence, or certain races (e.g., Asian patients) should avoid high doses of this drug. This drug contains lactose and should not be administered to patients with lactose intolerance or related genetic disorders. Caution should be taken for liver function abnormalities or muscle-related side effects when using this drug. In particular, those who consume large amounts of alcohol or have a history of liver disease should regularly have liver enzyme tests. If symptoms such as muscle pain, weakness, or cramps arise, inform a doctor immediately, and if necessary, check for muscle damage through blood tests. If muscle damage indicators are significantly elevated or symptoms become severe, this drug should be discontinued, and it may be resumed at a lower dose once symptoms improve. Furthermore, in the event of acute severe illness or worsening of certain bodily conditions, administration of this drug should be stopped, and if severe myasthenia gravis or ocular myasthenia occurs, usage should be ceased immediately. This drug may interact with other medications, so caution is needed, especially when combined with medications that pose a risk of muscle toxicity. When used with certain drugs, blood concentration of this drug may increase, raising the risk of side effects. Therefore, always consult a doctor or pharmacist about concomitant medications. The safety of this drug in pregnant or nursing women has not been established, thus it should not be used, and women capable of becoming pregnant should use appropriate contraception. In case of overdose, there are no specific antidotes, so treatment should be symptomatic, and liver function as well as muscle damage indicators should be monitored. This drug appears not to significantly affect driving or machine operation capability, but caution is advised as dizziness may occur.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, paleness, severe rash with fever, blisters, skin shedding, mouth/eye mucosal pain, shortness of breath or difficulty breathing, asthma attacks, abnormal breathing with cough and fever, yellowing of skin or eyes (jaundice), extreme malaise, sudden and severe headache, lightning headache, seizures, altered consciousness, visual disturbances, paralysis, urination

Mild side effects

• Dyspepsia
• pruritus
• headache
• dizziness
• constipation
• nausea
• abdominal pain
• herpes zoster
• vulvar pruritus
• itching

Store this drug in a tightly sealed container to prevent exposure to air and moisture, and it is safe to keep it at room temperature between 1 degree and 30 degrees Celsius. This storage method helps maintain the drug's effectiveness and prevents degradation.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/bottle