Empagliflozin and Metformin Extended-Release Tablets 25/1000 mg

Adult dose

The dosage of this medication is determined within the range of a maximum daily dose of 25 mg of Empagliflozin and 2000 mg of extended-release Metformin Hydrochloride, considering each patient's current treatment, efficacy, and tolerability. This medication is taken once daily in the evening with meals to reduce gastrointestinal side effects associated with Metformin. Increases in Metformin Hydrochloride dosage should proceed gradually, while maintaining the extended-release characteristics.

This medication is used for the treatment of diabetes and works by combining two main ingredients to help control blood sugar levels. However, caution is necessary while taking this medication. Severe lactic acidosis, a rare side effect, may occur, which can be life-threatening, so any symptoms must be reported to healthcare professionals immediately. Also, when taken with insulin or other diabetes medications, hypoglycemia may occur, so blood sugar levels must be monitored carefully. Patients with poor kidney function or those suffering from acute infections, serious heart issues, or liver dysfunction should avoid using this medication. Particularly, this medication should be temporarily discontinued before and after surgeries or imaging exams requiring iodinated contrast, and it should only be resumed once kidney function is verified to be normal. This medication may increase the risk of genital and urinary tract infections, so immediate treatment is necessary if symptoms appear. Additionally, this medication can lower Vitamin B12 levels, so long-term users should check their Vitamin B12 status with blood tests. Alcohol consumption should be avoided during treatment, particularly in patients with liver or kidney problems or dehydration. Elderly patients or those with reduced kidney function may need to adjust their medication dosage and regularly monitor kidney function. This medication should not be broken, chewed, or crushed; it must be swallowed whole, and there is no need to worry if the tablet's coating is expelled intact in stool. Serious side effects can occur in case of overdose; hence, the medication should be taken precisely as directed by a physician, and any suspected side effects should be discussed with a healthcare provider immediately. Finally, it is crucial to have regular blood tests and consultations with healthcare providers to continuously monitor health conditions while taking this medication.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, shedding skin, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, cough with fever and difficulty breathing, yellowing of skin or eyes (jaundice), profound lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, vision disturbances, paralysis, urination

Mild side effects

• Hypoglycemia
• urinary tract infection
• genital infection
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This medication must be stored in a tightly closed container to protect it from air and moisture. It's essential to maintain a storage temperature between 1 to 30 degrees Celsius to preserve the medication's efficacy and safety over time.

Appearance

Pale yellow, double convex, oval-shaped extended-release film-coated tablet

Package unit

30 tablets/bottle