JW Ibuprofen Premix Injection

Adult dosage

As an adjunct to narcotic analgesics (morphine) for moderate to severe pain control, 400mg-800mg is to be administered intravenously every 6 hours as needed. A maximum of 3200mg can be administered per day, with a minimum administration duration of 30 minutes. For antipyretic treatment, 400mg can be given intravenously every 4-6 hours as needed, following the initial dose of 400mg based on the patient's condition every 4 hours as necessary.

Children's dosage

For children aged 6 months to under 12 years, a single dose starting at 10mg/kg (maximum 400mg) should be administered intravenously every 4 to 6 hours as needed, with a minimum administration duration of 10 minutes. Maximum of 4 doses per day.

This medication may increase the risk of serious cardiovascular issues such as myocardial infarction or stroke in patients with cardiovascular diseases or risk factors. Therefore, these patients should carefully monitor their symptoms while taking this medication and consult a healthcare professional immediately if any adverse reactions occur. This medication can cause serious gastrointestinal adverse reactions such as gastrointestinal bleeding, ulcers, and perforations; therefore, special caution is required for the elderly or long-term users. If symptoms such as abdominal pain, bloody stools, or vomiting occur while taking this medication, the physician should be notified immediately. Patients with a history of gastrointestinal ulcers or bleeding, or those with severe hepatic, renal, or cardiac dysfunction should not take this medication. Furthermore, patients allergic to any component of this medication or those with a history of asthma should also avoid use. Patients with hematological abnormalities or bleeding tendencies, cirrhosis, renal impairment, heart diseases, and hypertension should be especially cautious during administration. It is also advisable for pregnant and lactating women to avoid this medication. This medication can cause various side effects including serious allergic reactions, skin rashes, hepatic dysfunction, hematological abnormalities, renal impairment, and respiratory distress; if any of these symptoms appear, immediate consultation with healthcare professionals is necessary. This medication should not be taken in excess of the recommended dosage, and it is safer not to take it in conjunction with other nonsteroidal anti-inflammatory drugs. Especially in patients with hypertension, blood pressure may rise or worsen, so blood pressure should be frequently monitored during early use and throughout the course of treatment. Patients with fluid retention or edema may experience worsening of their condition while taking this medication; hence, caution is required. Patients with impaired renal or hepatic function should undergo regular evaluations while taking this medication, and if any abnormal findings are detected, the dosage should be adjusted or the medication should be discontinued. This medication can interact with aspirin or anticoagulants, ACE inhibitors, diuretics, lithium, and methotrexate; therefore, patients taking these medications must inform healthcare professionals and exercise caution during use. During pregnancy, especially in the third trimester, it may be harmful to the fetus, so this medication should not be used during pregnancy, and lactating women should discontinue breastfeeding or consult with healthcare professionals if taking this medication. The safety and efficacy of this medication have not been established in children under 6 months of age, so its use is not recommended in this age group. Elderly patients may have reduced physical function, thereby increasing the risk of side effects when taking this medication, which necessitates dosage adjustment and monitoring. In the case of overdose, severe symptoms such as dizziness, vomiting, abdominal pain, renal failure, respiratory distress, and hypotension may occur; thus, strict adherence to the dosage is necessary, and if an overdose occurs, immediate medical attention should be sought.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash along with high fever, blisters, skin peeling, pain of oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), severe lethargy throughout the body, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination

Mild side effects

• Nausea
• vomiting
• bloating
• headache
• diarrhea
• drowsiness
• dizziness
• depression
• loss of appetite
• dyspepsia

This medication should be stored in a sealed container to prevent exposure to air, and it is best stored at room temperature between 1 degree and 30 degrees Celsius. Proper storage will maintain the medication's effectiveness and safety.

Appearance

Injection packed in a polypropylene, multilayer film plastic container as a clear colorless to pale yellow liquid

Package unit

104 milliliters/vial, 208 milliliters/vial