Empag Duo Extended Release Tablet 10/1000 mg (Empagliflozin, Metformin Hydrochloride)

Adult dose

The 25/1000 mg, 10/1000 mg extended-release tablets should be taken once daily, one tablet per dose. For patients taking the 12.5/1000 mg, 5/1000 mg extended-release tablets, they should take two tablets simultaneously once daily. The initial recommended dose is a total daily amount of 10 mg of empagliflozin and the existing dose of metformin, and if tolerance is good and additional blood glucose control is needed, empagliflozin may be increased.

This medication is used for treating diabetes and helps control blood glucose levels. However, it should not be administered to patients with impaired kidney function or liver dysfunction. Additionally, it should be avoided in situations such as acute infections, dehydration, heart diseases, and severe trauma. While taking this medication, there is a risk of hypoglycemia, so caution should be taken when used in combination with insulin or other hypoglycemic agents. Blood glucose levels and kidney function should be regularly monitored during treatment, especially in elderly patients or those with reduced kidney function. This medication can cause a rare but serious side effect known as lactic acidosis; therefore, if symptoms such as weakness, difficulty breathing, or abdominal pain occur, immediate medical attention should be sought. Also, there may be a risk of genital and urinary tract infections, so prompt treatment should be obtained if related symptoms appear. Discontinuation of this medication is required for a certain period when undergoing surgery or radiologic contrast examinations, and it should only be restarted once kidney function has returned to normal. The risk of side effects may increase when this medication is taken with alcohol, so avoiding alcohol is advisable. It is safer for pregnant women or those who may become pregnant not to use this medication, and it should be avoided during breastfeeding. When taking the medication, do not crush or chew the tablets; swallow them whole, although the coating may be visible in the stool, which is normal. During the treatment, symptoms of fluid loss or hypotension may occur, so preventing dehydration and ensuring adequate fluid intake is essential. Lastly, this medication's safety and efficacy have not been established in children, so it is recommended that it not be used in those under 18 years of age.

Serious side effects

Hives, angioedema, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe allergic reactions, severe rash with fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, severe skin reactions, difficulty breathing or shortness of breath, asthma attacks, respiratory distress with cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, liver dysfunction (jaundice), sudden and severe complications.

Mild side effects

Nausea, vomiting, diarrhea, abdominal pain, loss of appetite, constipation, altered taste, itching, rash, erythema, thirst, dizziness, headache, drowsiness, fatigue, facial swelling, edema, increased serum lipids, weight gain and loss, elevated blood pressure, insomnia, anxiety, depression, cough, upper respiratory infections, nasopharyngitis, soft tissue infections, pneumonia, skin lacerations, bruises, musculoskeletal pain, joint pain, and other common gastrointestinal and systemic symptoms.

This medication may be sensitive to air or moisture, so it should be stored in a sealed container. It is important to maintain a storage temperature between 1 to 30 degrees Celsius to ensure the medication's effectiveness and safety is preserved over time.

Appearance

Light orange oval extended-release film-coated tablet

Package unit

30 tablets/bottle