Medication info

Phytoben Cold Syrup

OTC medicationSyrup경구
Ingredient · strength
Acetaminophen›325mg / 1 packetTipepidine Citrate›20mg / 1 packetDL-Methylephedrine Hydrochloride›25mg / 1 packetChlorpheniramine Maleate›2.5mg / 1 packetGuaifenesin›83mg / 1 packetAnhydrous Caffeine›30mg / 1 packetRiboflavin Sodium Phosphate›4mg / 1 packet
Manufacturer / importer
동화약품(주)
Appearance
Orange transparent syrup contained in an aluminum pouch
Packaging
20 milliliters / pouch [x5]
Approval status
Active

MFDS item code 202401314 · Notified 2024.05.28

Summary

Main use
Relief of cold symptoms (runny nose, nasal congestion, etc.)
Who takes it
Adults · Children
Adult dose
For adults aged 15 years and above, take 1 pouch (20ml) three times a day after meals, 30 minutes after.
Child dose
For children aged 11 years to under 15 years, take 2/3 pouch three times a day after meals, 30 minutes after. For children aged 7 years to under 11 years, take 1/2 pouch three times a day after meals, 30 minutes after. For children aged 3 years and above ~

Ingredients

Manufacturer
동화약품(주)

Efficacy & effects

Relief of cold symptoms (runny nose, nasal congestion, etc.)

  • Runny nose
  • nasal congestion
  • sneezing
  • sore throat
  • cough
  • phlegm
  • chills
  • fever
  • headache
  • joint pain
  • muscle pain
View approved original text

This medication is used to relieve various symptoms of colds including runny nose, nasal congestion, sneezing, sore throat, cough, phlegm, chills, fever, headache, joint pain, and muscle pain.

How to take

Adult dose

For adults aged 15 years and above, take 1 pouch (20ml) three times a day after meals, 30 minutes after.

Child dose

For children aged 11 years to under 15 years, take 2/3 pouch three times a day after meals, 30 minutes after. For children aged 7 years to under 11 years, take 1/2 pouch three times a day after meals, 30 minutes after. For children aged 3 years and above ~

Precautions

This medicine can put a strain on the liver, so individuals who regularly consume more than three alcoholic drinks a day should consult a doctor or pharmacist before taking this medication. The ingredients in this medication can rarely cause serious skin reactions; therefore, if a rash or other allergic symptoms develop, discontinue use immediately and consult a specialist. Caution must be exercised not to exceed the maximum daily dose due to the presence of acetaminophen, and it should not be taken with other products containing acetaminophen. Those who have had hypersensitivity reactions to this medication, have a history of causing asthma, infants under three months old, or are currently taking or have recently stopped certain antidepressants or antipsychotics should not take this medication. It is safer to avoid taking this with other cold medications, antipyretics, sedatives, or antihistamines while using it. Particularly, children, individuals with a history of allergies, and those with liver, kidney, or heart conditions, as well as pregnant or nursing women, and individuals with gastrointestinal issues or specific chronic diseases should always consult a healthcare professional before taking this medication. If any abnormal symptoms such as rash, itching, vomiting, dizziness, or difficulty breathing occur during use, discontinue immediately and consult a doctor or pharmacist. Children under two years old should not take this medication except in special cases, and supervision by a guardian is necessary during use. It is essential to adhere to the prescribed dosage and avoid prolonged use, and to refrain from alcohol consumption while taking it. Additionally, drowsiness may occur while taking this medication, so driving or operating machinery should be avoided. Use of this medication in conjunction with certain antibiotics or drugs may increase the risk of side effects, so consultation with medical personnel is necessary before use. Finally, keep this medicine out of the reach of children, store it away from direct sunlight, and in a cool place with low humidity. Transferring the medication to another container for storage is to be avoided as it can lead to a decline in quality and risk of misuse.

Side effects and when to seek care immediately

Serious side effects

  • Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor → severe allergic reaction
  • Severe rash with high fever, blisters, skin peeling, pain in oral/eye mucosa → severe skin adverse reaction
  • Asthma
  • Profound lethargy, yellowing of skin or eyes (jaundice) → liver disorders (jaundice)

Mild side effects

Rash, redness (congestion), itching, nausea, vomiting, loss of appetite, constipation, swelling, difficulty urinating, dry mouth (persistent or severe), dizziness, anxiety, trembling, insomnia, high anion gap metabolic acidosis (HAGMA)

Not everyone experiences these, and they can vary from person to person.

Interactions

Drug interactions

This medication should not be taken in conjunction with MAO inhibitors (antidepressants, antipsychotics, emotional regulators, anti-Parkinson's drugs, etc.), cough suppressants, other cold medications, antipyretics, sedatives, or antihistamines. Do not use this medication within two weeks after stopping MAO inhibitors. Consult a doctor or pharmacist when taking diabetes medications, gout medications, arthritis medications, anticoagulants, or steroid medications.

Storage

This medication should be stored in a sealed container that blocks air and moisture and kept at room temperature between 1 degree and 30 degrees Celsius. Storing it this way maintains the effectiveness of the medicine and prevents deterioration.

Appearance and packaging

Appearance

Orange transparent syrup contained in an aluminum pouch

Package unit

20 milliliters / pouch [x5]

Questions about this medicine

  • QAfter taking it, I feel very thirsty and have difficulty urinating.

    The product information states that if you experience persistent or severe thirst or difficulty urinating, you should immediately stop taking it and consult a doctor or pharmacist. If symptoms persist, seek medical attention.

    Answers 1 · 2026.09.14

  • QWill it be alright to take motion sickness medication?

    It is stated that you should not take this medication together. The approval details indicate not to take it with oral medications containing antihistamines, such as anti-nausea medications and oral treatments for rhinitis; therefore, please consult your pharmacist before traveling.

    Answers 1 · 2026.09.14

  • QCan I take this if I have a cough with phlegm?

    This medication is approved for the relief of various cold symptoms such as runny nose, nasal congestion, cough, phlegm, and fever. For individuals aged 15 and older, the recommended dose is 1 sachet (20ml) taken 3 times a day 30 minutes after meals, and do not take it with other cough medications.

    Answers 1 · 2026.09.14

For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.