Alpedin 120 mg (Fexofenadine Hydrochloride)

Adult dose

Adults and adolescents aged 12 years and older should take 120 mg of fexofenadine hydrochloride orally once daily before meals with water. Elderly patients and those with liver failure do not require dosage adjustments. Patients with renal failure should take an initial dose of 60 mg orally once daily before meals with water.

Child dose

The safety and efficacy of this medication have not been established in children under 12 years of age.

This medication should not be used by patients who have shown allergic reactions to this medication or its components. Patients with impaired kidney function, elderly patients, and those with heart disease or a history of heart disease should use this medication with caution. The most common side effect of this medication is headache, and other possible side effects include drowsiness, dizziness, and nausea. Rarely, symptoms such as fatigue, insomnia, nervousness, sleep disturbances, nightmares, skin rash, hives, itching, angioedema, difficulty breathing, skin flushing, and systemic hypersensitivity reactions may occur; if these symptoms occur, consult a doctor immediately. Severe allergic reactions such as shock may occur; if symptoms such as difficulty breathing, low blood pressure, chest pain, or skin redness appear, discontinue the medication immediately and seek medical assistance. Liver function abnormalities may occur; if liver enzyme levels rise or jaundice symptoms appear, discontinue the medication and consult a doctor. This medication can affect the nervous system, leading to symptoms such as headache, dizziness, and nausea, so caution is advised. When driving or operating machinery, it is advisable to check individual responses to this medication before determining safety. This medication is not metabolized by the liver, so the potential for drug interactions due to liver metabolism is low, but caution is advised when taken with certain antibiotics or antifungals as they may increase serum concentrations. When taken with antacids containing aluminum or magnesium hydroxide, a minimum interval of 2 hours should be observed to prevent interference with the absorption of this medication. Taking this medication with grapefruit juice, orange juice, or apple juice may reduce its effectiveness, so it is recommended to take it with water. Women who are pregnant or may become pregnant should use this medication with caution after consulting a doctor, as safety for the fetus has not been established. Women who are breastfeeding should avoid using this medication, as it can be excreted in breast milk. Safety and efficacy in children under 12 years of age have not been sufficiently established, so caution is required for their use. In elderly patients, the risk of decreased kidney function is higher, so it is advisable to adjust the medication dosage and perform regular kidney function tests. This medication may affect allergy tests, so it should be discontinued prior to allergy skin testing. There are no specific reports of acute toxicity in cases of overdose, but symptoms such as dizziness, drowsiness, and dry mouth may appear, so appropriate treatment is needed based on symptoms. Store out of reach of children, and avoid transferring the medication to another container as it may lead to accidents or degradation of quality.

Serious side effects

• Hives
• angioedema
• chest tightness
• difficulty breathing
• chest discomfort
• systemic hypersensitivity reaction
• shock
• liver dysfunction
• jaundice

Mild side effects

• Headache
• drowsiness
• dizziness
• nausea
• fatigue
• insomnia
• nervousness
• sleep disturbances
• nightmares
• diarrhea

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is best to keep the storage temperature between 1 degree and 30 degrees Celsius to maintain the medication's effectiveness and safety over time.

Appearance

Pale pink oval film-coated tablet

Package unit

PTP packaging - 10 tablets/box [10 tablets/PTP x 1], bottle packaging - 30 tablets/bottle, bottle packaging - 100 tablets/bottle