TripM Duo Tablet 2.5/1000 mg (Linagliptin, Metformin)

Adult dose

This medication is administered twice daily with meals. 1. If there is no prior experience with metformin treatment: Take 1 tablet of this medication 2.5/500 mg twice daily, and can subsequently be increased to 1 tablet of 2.5/1000 mg twice daily. 2. If blood glucose control is difficult with metformin monotherapy: Administer 2.5 mg of linagliptin twice daily, along with the existing metformin dosage. 3.

This medication is used to control blood glucose levels. While taking this medication, there is a rare but serious side effect known as lactic acidosis, and therefore it should not be administered to patients with impaired kidney function or with problems related to the heart or liver. Additionally, this medication should not be used in pregnant or breastfeeding women, nor in situations such as acute infections or severe trauma that can quickly worsen kidney function. Due to the risk of hypoglycemia, careful monitoring of blood glucose changes is necessary when used in conjunction with insulin or sulfonylureas, and dosage adjustments of other medications may be required as needed. Elderly patients with decreased kidney function or certain conditions should regularly have kidney function tests, and the dosage may need to be adjusted based on their condition. If symptoms of acute pancreatitis or skin blisters such as vesicular pemphigoid appear, the medication should be immediately discontinued, and a doctor should be consulted. Avoid alcohol consumption during treatment, and consult with healthcare professionals as there may be interactions when taking other medications together. Safety and efficacy in children under 10 years have not been established, and its use is not recommended in this age group. The use of this medication should be temporarily halted before and after tests that can affect kidney function, such as surgery or radiological examinations. This medication may cause side effects such as gastrointestinal disturbances, fatigue, headaches, and dizziness, and if symptoms are severe or persistent, the doctor should be informed. Finally, this medication should be stored out of reach of children, kept away from moisture, and not transferred to another container.

Serious side effects

Hives, angioedema, lactic acidosis, pancreatitis, vesicular pemphigoid, liver function impairment (including jaundice), severe allergic reactions (chest tightness, difficulty breathing, cold sweat, paleness), cardiac disorders (congestive heart failure, angina, acute myocardial infarction, unstable angina, cardiac arrest), severe edema, difficulty breathing, asthma attacks, cerebral infarction, acute kidney injury, end-stage kidney disease, acute cholangitis, acute cholecystitis, cholangitis, acute pyelonephritis.

Mild side effects

Hypoglycemia, taste disorders, cough, decreased appetite, diarrhea, constipation, nausea, vomiting, abdominal pain, oral ulcer formation, abnormal liver function tests, hepatitis, pruritus, erythema, rash, musculoskeletal and connective tissue abnormalities, increased lipase, increased amylase, decreased and deficient vitamin B12, increased triglycerides in the blood, decreased hemoglobin, increased blood potassium, increased creatinine, increased blood creatine phosphokinase.

This medication should be stored in a tightly closed container to protect it from air and moisture. It is recommended to store it at room temperature, between 1 to 30 degrees Celsius, avoiding extremes in temperature.

Appearance

Pink, bilaterally convex, oval film-coated tablet

Package unit

30 tablets/bottle, 60 tablets/bottle