Medication info
Mebixat 20 mg (Memantine Hydrochloride)

Mebixat 20 mg (Memantine Hydrochloride)

Prescription medicationTablet경구
Ingredient · strength
Memantine Hydrochloride›20mg / 1 tablet
Manufacturer / importer
(주)비보존제약
Appearance
Pink oval film-coated tablet
Packaging
30 tablets/box [10 tablets/PTP x 3], 30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 202401043 · Approved 2024.04.30 · Insurance code 658204760

Summary

Main use
Treatment of moderate to severe Alzheimer's disease
Who takes it
Adults
Adult dose
This medication is taken orally once daily and should be taken at the same time each day. If necessary, it can be administered as a twice-daily regimen. The maximum daily dosage for adults is 20 mg, with an initial increase of 5 mg weekly for the first 3 weeks. First week (days 1-7): 5 mg once daily Second week (days 8-14): 10 mg once daily Third week (days 15-21): 15 mg once daily From the fourth week onward,

Ingredients

Manufacturer
(주)비보존제약

Efficacy & effects

Treatment of moderate to severe Alzheimer's disease

  • Moderate Alzheimer's disease
  • severe Alzheimer's disease
View approved original text

This medication is used to treat moderate to severe Alzheimer's disease. Alzheimer's disease is a condition characterized by a gradual decline in memory and cognitive function, and this medication helps alleviate these symptoms and improve the quality of life for patients. Regular use can slow the rate of cognitive decline. It is important for patients and caregivers to consult with a physician and adhere to the prescribed dosage. This medication effectively improves the symptoms of Alzheimer's disease.

How to take

Adult dose

This medication is taken orally once daily and should be taken at the same time each day. If necessary, it can be administered as a twice-daily regimen. The maximum daily dosage for adults is 20 mg, with an initial increase of 5 mg weekly for the first 3 weeks. First week (days 1-7): 5 mg once daily Second week (days 8-14): 10 mg once daily Third week (days 15-21): 15 mg once daily From the fourth week onward,

Precautions

This medication should not be used in patients with an allergy to its ingredients. It should not be administered to patients with severely impaired liver function or very poor kidney function. Use with caution in patients with epilepsy, a history of seizures, or those at high risk of seizures. Concurrent use with NMDA antagonists such as Amantadine, Ketamine, or Dextromethorphan may increase central nervous system side effects; avoid such combinations. Patients with factors that alter the acidity (pH) of urine should be monitored closely. Caution is warranted for patients with recent myocardial infarction, heart failure, or uncontrolled hypertension due to insufficient safety data. While taking this medication, side effects like dizziness, headache, constipation, drowsiness, and hypertension may occur; any unusual symptoms should be discussed with healthcare professionals. There may be interactions with other medications, especially when taken with Levodopa, anticholinergics, barbiturates, antipsychotic medications, muscle relaxants, and warfarin. Pregnant women or those who may become pregnant should consult with a physician regarding the potential risks to the fetus before use. Breastfeeding women are advised to discontinue breastfeeding as this medication may pass into breast milk. Safety and efficacy in children and adolescents under 18 have not been established. In cases of overdose, symptoms may include confusion, drowsiness, dizziness, hallucinations, seizures, vomiting, and diarrhea; seek medical treatment immediately. This medication may affect patients' mental functions, so caution is advised when driving or operating machinery. Store in a safe place out of reach of children and avoid transferring to other containers as it may adversely affect the quality.

Side effects and when to seek care immediately

Serious side effects

  • Seizures
  • psychotic reactions
  • hallucinations
  • heart failure
  • venous thromboembolism/thrombosis
  • dyspnea
  • pancreatitis

Mild side effects

  • Dizziness
  • headache
  • constipation
  • drowsiness
  • hypertension
  • confusion
  • hallucinations
  • psychotic reactions
  • balance disorders
  • gait abnormalities
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  • seizures
  • heart failure
  • venous thromboembolism/thrombosis
  • dyspnea
  • vomiting
  • pancreatitis
  • elevated liver function tests
  • hepatitis
  • fatigue

Not everyone experiences these, and they can vary from person to person.

Storage

This medication can be sensitive to air and moisture, so it should be stored in a tightly closed container. It is best to maintain storage temperatures between 1°C and 30°C room temperature. Proper storage can help retain the medication's efficacy and safety over time.

Appearance and packaging

Appearance

Pink oval film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP x 3], 30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.