RANIGLIPTIN Duo Sustained Release Tablet 5/1000 mg (Lina-gliptin, Metformin Hydrochloride)

Adult dose

This medication is to be taken once daily with the evening meal. To maintain its sustained release properties, it should be swallowed whole without breaking, crushing, grinding, or chewing. The 5/1000 mg sustained release tablet is taken once daily as one tablet. The 2.5/1000 mg sustained release tablet is taken once daily as two tablets. 1. If not currently treated with Metformin: The initial dosage is 5 mg of Lina-gliptin per day and [Metformin dosage not fully included].

This medication may rarely cause severe lactic acidosis and hypoglycemia, so caution is required. It should not be used in patients with severely impaired renal function, liver dysfunction, acute heart failure, or myocardial infarction. Patients with allergies to the ingredients of this medication or those with type 1 diabetes should also avoid its use. When used with other diabetes medications or insulin that can cause hypoglycemia, close monitoring of blood glucose changes is necessary, and dosage adjustments may be required. Lactic acidosis is a very serious side effect; if symptoms such as abdominal pain, myalgia, weakness, or dyspnea occur, notify a physician immediately. Regularly check renal function to ensure the safe administration of this medication, and take extra caution in elderly individuals or those at risk of impaired renal function. This medication should be temporarily discontinued before and after surgery or administration of radiographic iodine contrast, and resumed only after kidney function has recovered. Acute pancreatitis or skin blistering disorders may occur; if you experience severe abdominal pain or skin abnormalities during treatment, seek medical attention immediately. This medication should be taken during or after meals, and tablets should be swallowed whole without breaking, crushing, or chewing. Long-term use may decrease vitamin B12 levels, so it is advisable to check vitamin B12 status through blood tests. It is preferable to avoid this medication during pregnancy or breastfeeding, and patients planning a pregnancy should consult their physician. Interactions may occur when taken with other medications, so inform healthcare professionals of any other medications being taken. The safety and effectiveness of this medication in children have not been established, and dosing for elderly patients should consider renal function. In case of overdose, procedures should be taken to eliminate the drug from the gastrointestinal tract, and immediate treatment is necessary for lactic acidosis. This medication should be stored out of reach of children, away from moisture, and should not be transferred to other containers.

Serious side effects

Hives, angioedema, lactic acidosis, pancreatitis, similar dermatitis, angioedema, severe and disabling arthralgia, acute pancreatitis, angioedema, angioedema, chest tightness, difficulty breathing, severe swelling (edema), angioedema, abnormal liver function (liver function abnormalities, hepatitis), severe skin reactions (hives, rash, erythema), severe allergic reactions (hives, angioedema), respiratory issues (dyspnea, asthma attacks),

Mild side effects

Hypoglycemia, taste disturbance, cough, loss of appetite, diarrhea, constipation, nausea, vomiting, abdominal pain, oral ulcers, abnormal liver function, hepatitis, itching, erythema, rash, severe and disabling arthralgia, rhabdomyolysis, increased lipase, increased amylase, nasopharyngitis, allergic reactions, angioedema, abnormal results in vitamin B12 absorption tests, angioedema, similar dermatitis, gastrointestinal disorders, infections, immune system abnormalities, neurological disorders,

This medication must be stored in a tightly closed container to protect it from air and moisture. It is recommended to maintain the storage temperature between 1 and 30 degrees Celsius.

Appearance

Oval sustained release tablet, white to almost white, engraved with A501 on one side

Package unit

28 tablets/box (7 tablets/PTP x 4), 30 tablets/bottle