Saminon 30 mg (Nisergoline)

Adult dose

* 5 mg, 10 mg Adults: Administer 5 ∼ 10 mg of nicergoline orally per dose 2 ∼ 3 times daily before meals. Adjust the dose as appropriate according to symptoms. * 30 mg Adults: Administer 30 mg of nicergoline orally once daily before a meal. If the desired effect is not achieved at this dose, the dose may be increased to 60 mg. The dose may be reduced after symptoms improve. In patients with impaired renal function (serum creatinine >175 µmol/L) (2 mg/dL), administer a reduced dose.

This medication should not be used in certain patients. First, it should not be administered to patients allergic to this medication or to ergot alkaloids. Additionally, patients who have recently experienced a heart attack or have acute bleeding should not use this medication. Patients taking medications that affect the sympathetic nervous system, those with very slow heart rates, or those who have not fully stabilized after intracranial bleeding should also avoid this medication. Patients with symptoms of orthostatic hypotension need to be cautious as well. Patients with mild bradycardia or renal function issues should use this medication with greater caution. Rarely, this medication may cause symptoms such as indigestion, diarrhea, constipation, nausea, vomiting, abdominal pain, dry mouth. There may also be a temporary increase in liver function test results. Central nervous system abnormalities such as dizziness, blood pressure changes, drowsiness, headache, fatigue, and insomnia have been rarely reported. In addition, allergic reactions such as skin rashes, itching, and flushing may occur. When taken with other medications that lower blood pressure, the blood pressure may drop too low, so it is important to check the blood pressure frequently. This medication may affect uric acid levels, so patients with gout or hyperuricemia should be cautious. When driving or operating machinery after taking this medication, caution is advised due to potential drowsiness or dizziness. This medication is metabolized by specific enzymes in the liver, which may interact with other drugs that utilize the same metabolic pathway. Women who are pregnant or may become pregnant should carefully consider the risks and benefits of taking this medication. Animal studies have reported harmful effects on the fetus, and breastfeeding women should avoid this medication if possible or discontinue breastfeeding as it may be excreted in breast milk. Elderly patients may have weakened physical function, so dose reduction or careful administration is needed. Safety in children has not been established, so usage is not recommended. In cases of overdose, blood pressure may drop rapidly, so blood pressure should be monitored frequently, and necessary action should be taken. This medication should be stored out of reach of children and kept sealed in its original container for safety.

Loss of appetite, diarrhea, constipation, nausea, vomiting, nonspecific upper abdominal pain or cramps, dry mouth, elevated ALT, elevated AST, dizziness, orthostatic hypotension, hypertension, increased blood uric acid, blood pressure decrease, drowsiness, lethargy, headache, tinnitus, fatigue, insomnia, rash, hives, itching, flushing, sensation of heat, nightmares, mood disturbances, indigestion

This medication should be stored in a tightly closed container to avoid exposure to air or moisture, and it is safe to keep it at room temperature between 1 degree and 30 degrees Celsius. Storing it this way helps maintain the medication's effectiveness and prevents deterioration.

Appearance

Yellow film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle