Nisergol Tablet 30mg (Nisergoline)

Adult dose

* 5 mg, 10 mg Adults: Administer 5 ∼ 10 mg of nicergoline orally before meals 2 ∼ 3 times daily. Adjust the dose appropriately according to symptoms. * 30 mg Adults: Administer 30 mg of nicergoline orally once daily before a meal. If the desired effect is not achieved at this dose, the dose may be increased to 60 mg. The dose may be reduced after symptoms improve. In patients with impaired renal function (serum creatinine >175 µmol/L) (2 mg/dL), administer a reduced dose.

This medication should not be used in certain patients. For example, it should not be administered to individuals allergic to this medication or ergot alkaloids, patients with acute myocardial infarction, patients with acute bleeding, individuals taking sympathomimetic drugs, patients with very slow heart rates, patients with intracranial hemorrhage who have not completed hemostasis, and patients with orthostatic hypotension. Additionally, this medication should be used with caution in patients with slightly slow heart rates or impaired renal function. Gastrointestinal symptoms may rarely occur, such as loss of appetite, diarrhea, constipation, nausea, vomiting, abdominal pain or cramps, and dry mouth. Liver function test values may increase, and symptoms of circulatory system anomalies such as dizziness, orthostatic hypotension, hypertension, elevated blood uric acid levels, and blood pressure decrease may also occur rarely. Furthermore, symptoms related to the central nervous system, such as drowsiness, fatigue, headache, tinnitus, insomnia, and allergic reactions like skin rashes, urticaria, itching, flushing, and sensation of heat, may also appear rarely. When taken with other antihypertensive agents, the blood pressure-lowering effect may be enhanced, requiring frequent blood pressure monitoring. It may also affect uric acid metabolism, so caution is necessary for patients with a history of hyperuricemia or gout. After taking this medication, caution is advised when driving or operating machinery. This medication is metabolized in the liver, so it may interact with other drugs that affect liver metabolism. Pregnant women or women who may become pregnant should consult a doctor before taking this medication, as animal studies have reported potential harm to the fetus. Nursing mothers should either avoid taking this medication or discontinue breastfeeding. Elderly patients may have diminished bodily functions, so careful dosage adjustments are necessary, and its safety in pediatric patients has not been established. In case of overdose, blood pressure may temporarily drop, so blood pressure changes should be monitored and necessary actions taken. Finally, this medication should be stored out of reach of children, and must be stored sealed in its original container. Transferring it to another container may lead to misuse or deterioration of quality.

Loss of appetite, diarrhea, constipation, nausea, vomiting, occasional upper abdominal pain or cramps, dry mouth, increased ALT, increased AST, dizziness, orthostatic hypotension, hypertension, increased blood uric acid, hypotension, drowsiness, fatigue, headache, tinnitus, exhaustion, insomnia, rash, hives, itching, flushing, heat sensation, nightmares, mood disorders, dyspepsia

This medication may be sensitive to air and moisture, so it must be stored in a tightly sealed container. It is advisable to maintain the storage temperature between 1 degree and 30 degrees Celsius at room temperature. Storing it this way will help preserve the medication's efficacy for a longer time.

Appearance

Yellow round film-coated tablet

Package unit

Bottle packaging - 100 tablets/bottle, Bottle packaging - 30 tablets/bottle