Daewoong Nisergoline Tablets 30 mg (Nisergoline)

Adult dose

* 5 mg, 10 mg Adults: Administer 5 ∼ 10 mg of nicergoline orally 2 ∼ 3 times daily before meals. Adjust the dose as appropriate according to symptoms. * 30 mg Adults: Administer 30 mg of nicergoline orally once daily before a meal. If the desired effect is not achieved at this dose, it may be increased to 60 mg. The dose may be reduced after symptoms improve. Reduce the dose in patients with impaired renal function (serum creatinine >175 µmol/L) (2 mg/dL).

This medication should not be used in certain patients. Patients allergic to this medication or ergot alkaloids should not take it. Patients with acute problems related to the heart or acute bleeding may be at risk if they take this medication. Patients taking medications that affect the sympathetic nervous system and those with very slow heart rates should also refrain from using this product. Patients who have had bleeding in the head and have not fully achieved hemostasis or those with orthostatic hypotension should avoid this medication. Patients with mild bradycardia or renal impairment should use this drug cautiously. This medication may affect the digestive system and can rarely cause loss of appetite, diarrhea, constipation, nausea, vomiting, and abdominal pain. It may also affect liver function and elevate liver enzyme levels. Rarely, cardiovascular issues such as dizziness, orthostatic hypotension, and blood pressure changes may occur. Neurological symptoms such as drowsiness, fatigue, headache, and insomnia have also been reported. Additionally, hypersensitivity reactions such as rash, itching, and flushing may occur. Taking this medication with other antihypertensive drugs may enhance the blood pressure-lowering effect, so blood pressure should be monitored frequently. It may influence uric acid metabolism, so patients with a history of hyperuricemia or gout should be cautious. Care should be taken while driving or operating machinery after taking this medication. This drug is metabolized in the liver and may interact with other drugs that have the same metabolic pathway. Women who are pregnant or may become pregnant must consult a doctor before taking this medication. Animal studies have reported potential harm to the fetus, and breastfeeding women should avoid using this medication or discontinue breastfeeding as it may be excreted in breast milk. Elderly patients may have diminished physiological function, so dose adjustments may be necessary. Safety in children has not been established, so this medication should be used cautiously in pediatric patients. In the case of overdose, blood pressure may temporarily decrease, so blood pressure changes should be monitored and necessary actions taken. This medication should be kept out of reach of children and stored in its original container to maintain quality and prevent misuse.

• Loss of appetite
• diarrhea
• constipation
• nausea
• vomiting
• localized upper abdominal pain or cramps
• thirst
• elevated ALT
• elevated AST
• dizziness

This medication should be stored in an opaque container to prevent exposure to light and should be sealed to keep out air. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle