Abiraterone Duo Tablet 500/2.5 mg (Abiraterone, Prednisolone)

Adult dose

The recommended dose of this drug is 2 tablets (Abiraterone acetate 1,000 mg / Prednisolone 5 mg) once daily, and it must be taken on an empty stomach. Take at least 2 hours after a meal and avoid eating for at least 1 hour after taking the medication. The tablets should be swallowed whole with water. In case of liver function abnormalities, treatment should be withheld until liver function test results return to normal.

This drug should not be used by women who are pregnant or may become pregnant. Patients allergic to the ingredients in this medication should also not take it. Co-administration with Radium-223 dichloride can increase mortality and fracture risk, so it should be avoided. Patients with infections or weakened immune function may experience exacerbation of infections and require caution. Patients with severe liver dysfunction should not use this drug, and those with moderate to severe liver function should carefully consider the risks and benefits. Frequent liver function tests should be conducted, and if signs of liver damage occur, the medication should be discontinued. This medication may raise blood pressure, lower potassium levels in the blood, and cause fluid retention, so patients with heart or kidney disease should undergo regular blood pressure and blood tests. Additionally, symptoms of muscle damage such as myopathy or rhabdomyolysis may occur while taking this drug, so patients should consult their doctor if they experience muscle pain or weakness. Taking this drug with food may alter its effectiveness, so it must be taken on an empty stomach, and patients should inform their healthcare provider of any other medications they are taking due to potential interactions. As it contains corticosteroids, there is an increased risk of infections, and live vaccinations are prohibited. Long-term use may lead to side effects such as adrenal insufficiency, osteoporosis, hypertension, and diabetes, necessitating periodic testing. This drug is not intended for children, and caution should be exercised when used in older patients due to a higher risk of side effects. In case of overdose, medication should be stopped immediately, and appropriate treatment, including monitoring for arrhythmias and liver function, should be undertaken. Lastly, this medication should be stored out of reach of children and kept in its original container to maintain quality.

Serious side effects

Hives, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, pallor, severe rashes with high fever, blisters, skin peeling, pain in oral/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, jaundice (yellowing of the skin or eyes), profound lethargy, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, loss.

Mild side effects

• Itching
• sweating
• skin lesions
• skin peeling
• fatigue
• fever
• weakness
• facial swelling
• pain
• chest pain

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is best to maintain a storage temperature between 1 and 30 degrees Celsius to preserve its effectiveness.

Appearance

White, oval, film-coated tablet

Package unit

56 tablets/box [14 tablets/PTPX4]