Donghwa Nisergoline Tablets 30 mg (Nisergoline)

Adult dose

* 5 mg, 10 mg Adults: Administer 5 ∼ 10 mg of nicergoline orally 3 times daily before meals. Adjust the dose as appropriate according to symptoms. * 30 mg Adults: Administer 30 mg of nicergoline orally once daily before meals. If the desired effect is not achieved at this dose, the dose may be increased to 60 mg. The dose may be reduced after symptoms improve. For patients with impaired renal function (serum creatinine >175 µmol/L) (2 mg/dL), administer a reduced dose.

This medication should not be used in certain patients. Individuals allergic to this medication or ergot alkaloids should not take it. Patients with acute cardiac problems or acute bleeding should also avoid this medication. Patients taking medications that act on the sympathetic nervous system should not use this medication. Patients with very slow heart rates, those with incomplete hemostasis after intracranial hemorrhage, and those with symptoms of orthostatic hypotension should also avoid this medication. Patients with mild bradycardia or impaired renal function should use this medication with caution. Rarely, gastrointestinal disturbances such as loss of appetite, diarrhea, constipation, nausea, vomiting, abdominal pain, or dry mouth may occur with this medication. Liver function test results may temporarily rise. Cardiovascular abnormalities such as dizziness, orthostatic hypotension, changes in blood pressure, and increased serum uric acid levels may occur. CNS symptoms such as drowsiness, fatigue, headache, and insomnia may also rarely occur. Rarely, hypersensitivity reactions including rash, itching, and flushing may occur. Taking this medication with other antihypertensives may lead to excessively low blood pressure, so blood pressure should be monitored frequently. It may affect uric acid metabolism, so caution is advised for patients with a history of gout. Care should be taken when driving or operating machinery after taking this medication. This medication is metabolized in the liver, so there may be interactions with other drugs. Women who are pregnant or may become pregnant should use this medication with caution, and breastfeeding women should avoid taking it or consider stopping breastfeeding if possible. Elderly patients may require dosage adjustments due to decreased bodily functions. The safety of this medication in children has not been established, so its use is not recommended. In case of overdose, blood pressure may temporarily drop, so blood pressure changes should be carefully monitored and appropriate measures should be taken as necessary. This medication should be kept out of reach of children and stored in its original container, tightly sealed. Transferring it to another container may pose a risk of misuse or degradation in quality.

• Loss of appetite
• diarrhea
• constipation
• nausea
• vomiting
• localized upper abdominal pain or cramps
• thirst
• elevated ALT
• elevated AST
• dizziness

This medication may be sensitive to light, so it should be stored in a tightly sealed container that protects it from light. Additionally, it is best to store the medication at room temperature between 1°C and 30°C, avoiding excessively hot or cold environments.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle, 60 tablets/bottle