Niseon Tablet 30 mg (Nisergoline)

Adult dose

5 mg, 10 mg Adults: Administer 5 ∼ 10 mg of nicergoline orally per dose, 2 ∼ 3 times daily before meals. Adjust the dose as appropriate according to symptoms. 30 mg Adults: Administer 30 mg of nicergoline orally once daily before a meal. If the desired effect is not achieved at this dose, the dose may be increased to 60 mg. The dose may be reduced after symptoms improve. For patients with impaired renal function (serum creatinine >175 µmol/L) (2 mg/dL), administer a reduced dose.

This medication should not be administered to certain patients. For example, individuals allergic to this drug or ergot alkaloids, patients with acute myocardial infarction or acute bleeding, those taking sympathomimetic drugs, individuals with very slow heart rates, patients who have not completed hemostasis after intracranial hemorrhage, and patients with orthostatic dysregulation should not use it. Additionally, patients with mild bradycardia or renal function issues should use this medication cautiously. During treatment, rare gastrointestinal symptoms such as loss of appetite, diarrhea, constipation, nausea, vomiting, abdominal pain, and dry mouth may occur. There is also a possibility of elevated liver enzyme levels affecting liver function. Cardiovascular symptoms such as dizziness, orthostatic dysregulation, and changes in blood pressure may occur rarely, as well as central nervous system symptoms such as drowsiness, headache, fatigue, and insomnia. Allergic reactions such as rash, itching, and flushing may also occur, so caution is necessary. When this medication is taken with other antihypertensive drugs, blood pressure may drop too low, so blood pressure should be monitored frequently. Moreover, this medication can influence uric acid metabolism, and patients with gout or hyperuricemia should exercise caution. After taking this medication, one should be careful while driving or operating machinery, and it is essential to inform about any other medications being taken, as interactions may occur. Women who are pregnant or may become pregnant should use this medication with caution, and breastfeeding mothers should avoid using this medication if possible or discontinue breastfeeding as it may be secreted in breast milk. Elderly patients may have weakened bodily functions, so careful dose adjustment is necessary. The safety in children has not yet been established, so it is advisable not to use it. In case of overdose, blood pressure may temporarily drop, so blood pressure changes should be monitored, and necessary actions should be taken. Lastly, this medication should be stored out of reach of children and kept tightly closed in its original container.

• Loss of appetite
• diarrhea
• constipation
• nausea
• vomiting
• localized upper abdominal pain or cramps
• thirst
• elevated ALT
• elevated AST
• dizziness

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. In addition, it should be kept at room temperature, avoiding extreme heat or cold, ideally between 1°C and 30°C, to maintain its efficacy and safety.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle