Latuda 40 mg Tablets (Lurasidone Hydrochloride)

Adult dosage

Administer with food or after meals. 1. Schizophrenia: start with 40 mg once daily, using within the total daily range of 40 to 160 mg. The maximum daily dose is 160 mg. 2. Major depressive episode in type 1 bipolar disorder: start with 20 mg once daily as monotherapy or adjunct therapy with lithium/valproate, using within the total daily range of 20 to 120 mg. The maximum daily dose

Children's dosage

1. Adolescents aged 13 years and older with schizophrenia: start with 40 mg once daily, and use within the total daily range of 40 to 80 mg. The maximum daily dose is 80 mg. 2. Children aged 10 years and older

This medication should not be used in elderly patients with dementia-related psychosis due to an increased risk of death. There may be an increase in suicidal thoughts or actions during treatment, so patients' conditions should be closely monitored, especially during the initial months of treatment and when changing dosages. This medication can cause a serious side effect called neuroleptic malignant syndrome, characterized by high fever, muscle rigidity, and changes in mental status; if any of these symptoms occur, discontinue use immediately and inform medical personnel. Long-term use may lead to tardive dyskinesia, an irreversible movement disorder; if symptoms appear, consider discontinuing the medication. This medication may increase blood sugar levels, so patients with diabetes or those at risk of diabetes should monitor their blood sugar levels regularly. Elderly patients with dementia may have a higher risk of cerebrovascular adverse reactions such as stroke; therefore, this medication is not used for the treatment of dementia-related psychosis. Patients with allergies to this medication or its components, or those taking drugs that strongly inhibit or induce the enzyme (CYP3A4) responsible for metabolizing drugs in the liver should not use this medication. Patients with impaired kidney or liver function, those with diabetes, patients with low white blood cell counts or a history of leukopenia, those at risk of hypotension, patients with a history of seizures, and pregnant or breastfeeding women should use this medication with caution. This medication may cause drowsiness, nausea, vomiting, insomnia, anxiety, muscle rigidity, tremors, and other side effects, which may occur more frequently with higher doses. Other reported side effects include weight gain, increased prolactin levels, elevated blood pressure, indigestion, constipation, etc., so regular health monitoring is necessary. It is important to consult medical personnel immediately if any unusual symptoms occur during the use of this medication.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory difficulties accompanied by cough and fever, yellowing of the skin or eyes, extreme lethargy, sudden severe headache, lightning headache, seizures, confusion, visual disturbances, paralysis, markedly decreased urine output,

Mild side effects

• Nausea
• vomiting
• indigestion
• excessive salivation
• back pain
• drowsiness
• inability to sit still
• extrapyramidal symptoms
• dizziness
• insomnia

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture. It is important to maintain the storage temperature between 1°C and 30°C to ensure the effectiveness of the medication.

Appearance

White to grayish-white round film-coated tablets

Package unit

30 tablets/bottle, 90 tablets/bottle