Empaglin Duo Tablet 12.5/500 mg (Empagliflozin, Metformin Hydrochloride)

Adult dose

The recommended dose is 1 tablet once, twice daily. The dose should be determined based on the patient’s treatment regimen, efficacy, and tolerability within the range not exceeding 25 mg of empagliflozin and 2000 mg of metformin. If blood glucose control is insufficient with monotherapy of metformin or in combination with insulin, it is recommended to take 5 mg of empagliflozin twice daily and to continue with the usual dose of metformin. If tolerability is good and additional blood glucose control is necessary...

This medication helps control blood glucose and is used for diabetes treatment. However, during its use, a rare complication called lactic acidosis may occur, so caution is advised. Lactic acidosis is a serious condition that arises when too much lactic acid accumulates in the body, with symptoms including fatigue, muscle pain, difficulty breathing, and abdominal pain. This medication should not be administered to patients with poor kidney function, acute infections, dehydration, or severe heart disease. Additionally, it is also advised that patients with type 1 diabetes or women who are pregnant or nursing do not use this medication for safety. When used alongside other diabetes treatments, hypoglycemia may occur, so dosage adjustment is necessary if insulin or sulfonylurea medications are taken together. During treatment, regular monitoring of kidney function is essential to ensure the safe use of the medication. This medication may cause side effects such as urinary tract infections, genital infections, and increased urination, so if symptoms appear, consult with a doctor. Also, gastrointestinal disturbances, liver function abnormalities, hypoglycemia, fluid loss, and other adverse reactions have been reported, so caution is required. Prior to surgery or radiological examinations, this medication should be temporarily halted, and after confirming normal kidney function following the examination, it can be resumed. Alcohol consumption should be avoided as it may increase the risk of lactic acidosis. Elderly patients or those at risk for fluid loss should use this medication with increased caution and require regular health assessments. Women who are pregnant or may become pregnant and those who are nursing should not take this medication. In case of overdose, seek immediate medical attention for proper treatment, which may include hemodialysis. This medication is not recommended for children and should be kept out of reach of children.

Serious side effects

• Hives
• severe swelling (edema)
• ketoacidosis
• lactic acidosis
• angioedema
• perineal necrosis
• urosepsis
• pyelonephritis
• severe allergic reactions
• severe skin reactions

Mild side effects

• Hypoglycemia
• urinary tract infections
• genital infections
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

Store this medication in a tightly closed container to protect it from air and moisture. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

Brownish-purple, bilaterally convex oval film-coated tablet

Package unit

10 tablets/box [(10 tablets/PTP×1)], 60 tablets/box [(10 tablets/PTP×6)], 60 tablets/bottle