Empagliflozin/Metformin Tablets 12.5/1000 mg

Adult dose

The recommended dosage of this medication is 1 tablet once, twice daily. The maximum recommended daily dosage for each ingredient is up to 25 mg of empagliflozin and 2000 mg of metformin, and it should be determined considering each patient's current treatment regimen, effectiveness, and tolerance. For patients who cannot achieve sufficient blood sugar control with metformin alone or in combination therapy with other medications such as insulin, the recommended dosage is empagliflozin 5

This medication can cause serious side effects such as severe lactic acidosis, so it should be avoided in patients with impaired kidney function or severe infections, dehydration, heart problems, etc. When used in conjunction with other diabetes medications, there may be an increased risk of hypoglycemia, so caution is necessary. Regular monitoring of kidney function is required, and the use of this medication should be discontinued if there is a significant decline in kidney function. Before and after undergoing tests that involve iodinated contrast media, this medication should be temporarily discontinued, and it should be resumed only after confirming normal kidney function. Pregnant women or those who may become pregnant, and breastfeeding women should not use this medication. This medication may increase the risk of urinary tract infections or genital infections, so patients should consult a doctor immediately if any symptoms of infection appear. Hypoglycemia symptoms may occur, so patients should periodically check their blood sugar levels, especially when using insulin or sulfonylurea medications, and dose adjustments may be necessary. Use of this medication should be done cautiously in situations where there is a risk of fluid loss or dehydration, and doses may be temporarily stopped if symptoms are present. Patients with impaired liver function should also avoid using this medication, and regular check-ups are needed if liver disease is suspected. Vitamin B12 levels may decrease, so patients taking this medication long-term should have regular blood tests. In the case of overdose, serious side effects such as lactic acidosis may occur, and immediate medical attention is required, and hemodialysis treatment may be necessary if needed. It is advisable to avoid alcohol consumption while taking this medication, and in special circumstances such as acute illness, surgery, or trauma, it should be temporarily discontinued and a doctor should be consulted. Elderly or frail patients may have a decline in kidney function, so dose adjustments and regular kidney function tests are necessary. The safety and efficacy of this medication have not been confirmed in children, so it is not recommended for those under 18 years of age. The impact on driving or operating machinery is unclear, so caution may be necessary depending on symptoms. Patients taking this medication should be careful about foot care, and if there are any wounds or infections on the feet, they should notify medical personnel immediately. If any abnormal symptoms such as pain, swelling, or redness occur in the perineum, immediate medical attention should be sought, and treatment should be discontinued in severe cases.

Serious side effects

Urticaria, angioedema, perineal necrosis, ketoacidosis, lactic acidosis, severe allergic reactions, severe skin abnormal reactions, difficulty in breathing, asthma, abnormal liver function (jaundice), severe neurological symptoms, sudden and very severe headaches, visual disturbances, paralysis, severe swelling of the whole body with elevated blood pressure, severe edema or urination abnormalities, severe rash, blisters, skin peeling, pain of the oral/ocular mucosa, breathing difficulties or respiratory disturbances, acute

Mild side effects

• Hypoglycemia
• urinary tract infections
• genital infections
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This medication should be stored in a sealed container as it may be sensitive to air or moisture. It is recommended to maintain storage temperatures between 1 and 30 degrees Celsius to preserve the medication's efficacy for a longer period.

Appearance

Dark brownish-purple, oval biconvex film-coated tablet

Package unit

10 tablets/box (10 tablets/PTP x 1), 60 tablets/box (10 tablets/PTP x 6), 60 tablets/bottle