Empagduo Tablet 12.5/500 mg

Adult dose

The recommended dosage of this medication is 1 tablet at a time, twice a day. This is determined within the limits of the maximum recommended daily doses for each ingredient, which are empagliflozin 25 mg and metformin 2000 mg. For patients on metformin alone or other medications like insulin, the recommended dosage is empagliflozin 5 mg twice daily (total 10 mg) along with the usual dose of metformin. For those with good tolerance and where additional blood sugar control is needed, dosage can be increased to empagliflozin 25 mg (total daily).

This medication assists in the regulation of blood sugar. However, caution is needed as a rare side effect known as severe lactic acidosis may occur. Care should be taken if taken with other diabetes medications, as hypoglycemia may happen. This medication should not be used in certain patients. For instance, individuals with allergies to this drug or its components, those with severely impaired kidney function, acute infections, or dehydration should not take it. Additionally, individuals with type 1 diabetes or acute metabolic acidosis, as well as pregnant or breastfeeding women, should not take this medication. Patients with slightly impaired kidney function or at risk of fluid loss should use this medication cautiously. In particular, when used with insulin or sulfonylureas, dosage adjustments may be needed to reduce the risk of hypoglycemia. Irregular meals, intense exercise, and interactions with other drugs should also be monitored. Side effects such as hypoglycemia, urinary tract infections, genital infections, increased urination, gastrointestinal disturbances may occur when taking this medication. In particular, caution is needed, especially when used with insulin, as this can increase the risk of hypoglycemia. Lactic acidosis is a rare but very serious side effect; symptoms such as fatigue, muscle pain, difficulty breathing, or abdominal pain should prompt immediate medical attention. Additionally, metabolic issues like ketoacidosis can occur, requiring immediate treatment if symptoms such as vomiting, loss of appetite, abdominal pain, or difficulty breathing arise. This medication may affect body hydration status, so patients at risk for dehydration or hypotension should be particularly cautious. Patients with poor liver function or heart failure should consult a doctor before taking this medication. Pregnant or breastfeeding women should not take this medication, and it is not recommended for children under 18 years of age. Elderly patients may have a risk of reduced kidney function, so regular testing is required, and dosage adjustments may be necessary. In case of overdose, there is a risk of lactic acidosis, so immediate medical treatment is required, and blood dialysis may be necessary. This medication should be stored out of reach of children and kept in its original container for safety.

Serious side effects

Urticaria, angioedema, severe swelling (edema), severe allergic reactions, severe rashes, blisters, skin peeling, pain in oral/ocular mucosa, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough+fever, jaundice, liver abnormalities, sudden and very severe headaches, thunderclap headaches, seizures, confusional states, vision abnormalities, paralysis, serious neurological symptoms, significant reduction in urine output, total

Mild side effects

• Hypoglycemia
• urinary tract infections
• genital infections
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This medication should be stored in a sealed container to prevent exposure to air or moisture. It is best to maintain a storage temperature between 1 and 30 degrees Celsius (room temperature).

Appearance

Biconvex oval film-coated tablet with a light brownish-purple color

Package unit

60 tablets/bottle, 10 tablets/box [10 tablets/PTP x 1], 60 tablets/box [10 tablets/PTP x 6]