Empagliflozin/Metformin Tablet 12.5/500 mg

Adult dose

The recommended dosage of this medication is 1 tablet taken twice a day. The dosage should be determined within the maximum recommended daily doses of empagliflozin 25 mg and metformin 2000 mg for each component. For patients with inadequate blood sugar control, they should take empagliflozin 5 mg twice daily (total daily dose of 10 mg) along with their existing metformin dosage. If the tolerance is excellent and additional blood sugar control is needed, empagliflozin can be increased.

This medication may cause serious side effects, such as severe lactic acidosis, and patients must notify their physician immediately if symptoms occur. Additionally, it may increase the risk of hypoglycemia if used with insulin or sulfonylureas, so caution is advised. It should not be used in patients with moderate to severe renal impairment or certain acute illnesses. Treatment should be discontinued for a period before and after surgery or radiographic contrast tests, and can only be resumed after renal function has normalized. Women who are pregnant or breastfeeding should not take this medication. This medication may increase the risk of urinary tract infections and genital infections, so immediate treatment is necessary if infection symptoms occur. Patients with signs of fluid volume loss or dehydration must exercise caution when taking this medication, and especially the elderly should regularly monitor their renal function. Regular blood tests are recommended as vitamin B12 deficiency can occur. Alcohol consumption may increase the risk of lactic acidosis, so it should be avoided. Because there is a risk of hypoglycemia, meals should be taken regularly, and dosage adjustments may be necessary when used with other hypoglycemic agents. Caution is advised when driving or operating machinery while taking this medication, and any unusual symptoms should be reported to a physician immediately. This medication is not recommended for children, and dosage adjustments and monitoring of renal function are important for the elderly. In cases of overdose, immediate medical attention is required, and dialysis may be beneficial. This medication should be stored in its original container and kept out of reach of children.

Serious side effects

Hives, severe swelling (edema), angioedema, chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, peeling skin, pain in mucous membranes of mouth/eyes, difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of skin or eyes), profound lethargy, sudden severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances

Mild side effects

Urinary tract infections, genital infections, increased urination, nausea, vomiting, diarrhea, abdominal pain, loss of appetite, constipation, abnormal liver function tests, hepatitis, altered taste, rash, thirst, increased serum lipids, increased serum creatinine, increased hematocrit, hypoglycemia (when co-administered with insulin and/or sulfonylureas), decreased fluid volume, itching, rash, headache, dizziness, weight loss, insomnia, fever, chest discomfort, chest pain, weakness, oral discomfort

This medication should be stored in a tightly closed container to protect it from air and moisture. Additionally, it should be kept in a location that avoids extremes of temperature, ideally at room temperature between 1 and 30 degrees Celsius.

Appearance

Biconvex oval film-coated tablet, purple with a light brown tint

Package unit

Bottle packaging - 60 tablets/bottle, PTP packaging - 60 tablets/box [(10 tablets/PTP X 6)], PTP packaging - 10 tablets/box [(10 tablets/PTP X 1)]