Levocase Tablets (Montelukast Sodium, Levocetirizine Hydrochloride)

Adult dose

Adults and adolescents aged 15 years and older take 1 tablet orally once a day in the evening.

This medication can cause significant neuropsychiatric adverse effects, so if changes such as agitation, anxiety, depression, hallucinations, or suicidal thoughts occur during use, consult a doctor immediately. Patients allergic to this drug or its components, or to hydroxyzine and piperazine derivatives should not take this medication. Patients with severely impaired kidney function or undergoing dialysis, and women who are pregnant or breastfeeding should not use this medication. Patients with lactose intolerance or specific genetic metabolic disorders should also refrain from taking this medication. Elderly patients or those with impaired kidney or liver function should take this medication with caution, as the components may remain in the body longer and have effects. During the use of this medication, side effects such as upper respiratory tract infections, rhinitis, gastrointestinal disturbances, headaches, drowsiness, and skin rashes may occur, so if any abnormal symptoms persist, consult a healthcare professional. This medication is not used to treat acute asthma attacks; thus, appropriate emergency medication should be prepared for emergency situations, and abrupt switching to other steroid preparations should be avoided. Patients with hypersensitivity to aspirin or nonsteroidal anti-inflammatory drugs should avoid using those medications while taking this medication. Drowsiness or fatigue may occur during use, requiring attention when driving or operating machinery, and it is advisable not to use alcohol or central nervous system depressants concurrently. This medication has few interactions with other drugs; however, monitoring is needed if used in conjunction with certain medications as directed by a physician. It is safest to avoid using this medication during pregnancy or breastfeeding; if necessary, consult a doctor for cautious decision-making. Children under 15 years of age should not use this medication as its safety and efficacy have not been established. In case of overdose, there is no specific antidote, so appropriate treatment should be provided based on symptoms, and this medication is sensitive to light, so it should be prepared for use immediately after opening. When storing, keep out of reach of children and do not transfer to other containers.

Serious side effects

Urticaria, facial swelling, difficulty breathing, worsening asthma, eosinophilia, vasculitic rash, worsening pulmonary symptoms, cardiac complications, neuropathy, suicidal ideation and behavior, suicidal thoughts, suicide, significant neuropsychiatric adverse events (agitation, aggressive behavior, anxiety, depression, disorientation, attention disorders, stuttering, hallucinations, insomnia, memory disorders, obsessive-compulsive disorder, psychomotor hyperactivity, sleepwalking, tics, confusion, visual disturbances, paralysis, seizures

Mild side effects

• Upper respiratory tract infections
• nasopharyngitis
• gastrointestinal disturbances
• tonsillitis
• dry mouth
• QT prolongation
• hypercholesterolemia
• gastric cancer
• Alzheimer's dementia
• hypoperfusive cerebral infarction

This medication is sensitive to air and moisture, so it should be stored in a tightly sealed container. A storage temperature between 1 to 30 degrees Celsius is recommended.

Appearance

Beige colored round film-coated tablets

Package unit

28 tablets/PTP[(7 tablets/PTP*4)]