Cotrutene Nasal Spray
Oxymetazoline Hydrochloride 0.05g · Chlorpheniramine Maleate 0.25g
Solution · OTC medication · Combination
Kyungdong Pharmaceutical Co., Ltd.
MFDS item code 202302474 · Notified 2023.08.21
Relief of nasal congestion and rhinorrhea due to common cold (acute rhinitis) and allergic rhinitis
This medication is used to relieve symptoms such as nasal congestion, rhinorrhea, sneezing, and heavy head associated with common cold, allergic rhinitis, and sinusitis.
For individuals aged 7 and older and adults, spray 1-2 times into each nostril 1-2 times a day. The interval between applications should be 10-12 hours, and it should not exceed 2 applications within 24 hours.
For children aged 7 and older, spray 1-2 times into each nostril 1-2 times a day. The interval between applications should be 10-12 hours, and it should not exceed 2 applications within 24 hours.
This medication should not be used in children under 7 years old or infants under 2 years old. It should also not be used by individuals who are allergic to this medication or its components, or have experienced hypersensitivity reactions. Additionally, it should not be used by anyone taking or who has stopped taking MAO inhibitors, such as certain antidepressants or antipsychotics, within the past 2 weeks. Before using this medication, individuals with a history of allergies or previous allergic reactions to medications should consult a doctor or pharmacist. Those with conditions such as hypertension, heart disease, diabetes, thyroid issues, or glaucoma should also consult a specialist before using. Women who are pregnant or may become pregnant should consult a healthcare professional before using this medication. Consultation with a specialist is necessary if undergoing treatment for any reason or if cough persists for a long time or certain symptoms accompany it. This medication contains propylene glycol; those allergic to this component should take caution. If symptoms such as skin rash, redness, swelling, itching, or irritation occur while using, discontinue use immediately and consult a healthcare professional. If symptoms do not improve after using for more than 3 days, seek professional advice. It is essential to adhere to the prescribed dosage and usage; excessive use may worsen nasal congestion. It is only to be used for treating rhinitis and should not be applied to the eyes or ears. Avoid concurrent use and do not use continuously for more than 7 days. Drowsiness may occur during use, so caution should be taken when driving or operating machinery, and alcohol should be avoided. When used in children, supervision by an adult is necessary. The medication contains benzalkonium chloride, which may cause nasal mucosal irritation or swelling with prolonged use, so caution is advised. When storing, keep out of reach of children, away from direct sunlight, and in a cool, dry place. Do not transfer to another container, and take care to prevent misuse and maintain quality.
Swelling (severe edema), hives
Not everyone experiences these, and they can vary from person to person.
This medication should not be used by anyone who is taking or has stopped taking MAO inhibitors used for treating depression or Parkinson's disease within the last 2 weeks.
Do not consume alcohol while using this medication.
This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. Additionally, it is recommended to store it at room temperature, ideally between 1 to 30 degrees Celsius, that is neither too hot nor too cold.
Colorless or whitish liquid
20 milliliters/bottle
Even with the same ingredient, strength, dosage form and how it is taken can differ.
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Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.
QCan I use this if I have asthma?
Answers 1 · 2026.09.14
QIs it alright to have a drink after applying this?
Answers 1 · 2026.09.14
For anything that needs medical judgment, consult a doctor or pharmacist.
This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.