Medication info

Cotrutene Nasal Spray

OTC medicationSolution비강
Ingredient · strength
Oxymetazoline Hydrochloride›0.05g / 100mLChlorpheniramine Maleate›0.25g / 100mL
Manufacturer / importer
경동제약(주)
Appearance
Colorless or whitish liquid
Packaging
20 milliliters/bottle
Approval status
Active

MFDS item code 202302474 · Notified 2023.08.21

Summary

Main use
Relief of nasal congestion and rhinorrhea due to common cold (acute rhinitis) and allergic rhinitis
Who it is sprayed on
Adults · Children
Adult use
For individuals aged 7 and older and adults, spray 1-2 times into each nostril 1-2 times a day. The interval between applications should be 10-12 hours, and it should not exceed 2 applications within 24 hours.
Child use
For children aged 7 and older, spray 1-2 times into each nostril 1-2 times a day. The interval between applications should be 10-12 hours, and it should not exceed 2 applications within 24 hours.

Ingredients

Manufacturer
경동제약(주)

Efficacy & effects

Relief of nasal congestion and rhinorrhea due to common cold (acute rhinitis) and allergic rhinitis

  • Common cold
  • acute rhinitis
  • allergic rhinitis
  • sinusitis
  • nasal congestion
  • rhinorrhea
  • sneezing
  • heavy head
View approved original text

This medication is used to relieve symptoms such as nasal congestion, rhinorrhea, sneezing, and heavy head associated with common cold, allergic rhinitis, and sinusitis.

How to spray

Adult use

For individuals aged 7 and older and adults, spray 1-2 times into each nostril 1-2 times a day. The interval between applications should be 10-12 hours, and it should not exceed 2 applications within 24 hours.

Child use

For children aged 7 and older, spray 1-2 times into each nostril 1-2 times a day. The interval between applications should be 10-12 hours, and it should not exceed 2 applications within 24 hours.

Precautions

This medication should not be used in children under 7 years old or infants under 2 years old. It should also not be used by individuals who are allergic to this medication or its components, or have experienced hypersensitivity reactions. Additionally, it should not be used by anyone taking or who has stopped taking MAO inhibitors, such as certain antidepressants or antipsychotics, within the past 2 weeks. Before using this medication, individuals with a history of allergies or previous allergic reactions to medications should consult a doctor or pharmacist. Those with conditions such as hypertension, heart disease, diabetes, thyroid issues, or glaucoma should also consult a specialist before using. Women who are pregnant or may become pregnant should consult a healthcare professional before using this medication. Consultation with a specialist is necessary if undergoing treatment for any reason or if cough persists for a long time or certain symptoms accompany it. This medication contains propylene glycol; those allergic to this component should take caution. If symptoms such as skin rash, redness, swelling, itching, or irritation occur while using, discontinue use immediately and consult a healthcare professional. If symptoms do not improve after using for more than 3 days, seek professional advice. It is essential to adhere to the prescribed dosage and usage; excessive use may worsen nasal congestion. It is only to be used for treating rhinitis and should not be applied to the eyes or ears. Avoid concurrent use and do not use continuously for more than 7 days. Drowsiness may occur during use, so caution should be taken when driving or operating machinery, and alcohol should be avoided. When used in children, supervision by an adult is necessary. The medication contains benzalkonium chloride, which may cause nasal mucosal irritation or swelling with prolonged use, so caution is advised. When storing, keep out of reach of children, away from direct sunlight, and in a cool, dry place. Do not transfer to another container, and take care to prevent misuse and maintain quality.

Side effects and when to seek care immediately

Serious side effects

Swelling (severe edema), hives

Mild side effects

  • Rash
  • redness (erythema)
  • irritation
  • itching
  • drowsiness
  • nasal irritation
  • swelling
  • nasal mucosal edema

Not everyone experiences these, and they can vary from person to person.

Interactions

Drug interactions

This medication should not be used by anyone who is taking or has stopped taking MAO inhibitors used for treating depression or Parkinson's disease within the last 2 weeks.

Food interactions

Do not consume alcohol while using this medication.

Storage

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. Additionally, it is recommended to store it at room temperature, ideally between 1 to 30 degrees Celsius, that is neither too hot nor too cold.

Appearance and packaging

Appearance

Colorless or whitish liquid

Package unit

20 milliliters/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

  • QCan I use this if I have asthma?

    This medicine contains benzalkonium chloride, which may cause bronchospasms. If you have respiratory diseases such as asthma, please consult your doctor or pharmacist before use.

    Answers 1 · 2026.09.14

  • QIs it alright to have a drink after applying this?

    The product leaflet specifies not to consume alcohol while using this medicine, so it is better to avoid drinking. Additionally, if you are currently taking or have stopped taking an MAO inhibitor within the past 2 weeks, you should not use this medication.

    Answers 1 · 2026.09.14

For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.