Sitaglutin Tablet 100 Milligrams (Sitagliptin Hydrochloride Hydrate)

Adult dose

The standard dosage for this drug, either as monotherapy or in combination therapy, is one 100 mg tablet once daily, with a maximum daily dose of 100 mg. For patients with renal impairment, dosage adjustments are necessary according to renal function. In mild to moderate renal impairment patients (eGFR 45 to less than 90), no dosage adjustment is necessary. In moderate renal impairment patients (eGFR 30 to less than 45), the dosage is 50 mg once daily. In severe renal impairment patients

This medication can cause severe allergic reactions; if you notice sudden skin rashes, difficulty breathing, or swelling of the face or neck after taking this medication, stop taking it immediately and consult a doctor. While taking this medication, there is a possibility of developing a serious condition called pancreatitis, which is an inflammation of the pancreas, so if symptoms such as abdominal pain, nausea, or vomiting appear, inform healthcare personnel immediately. This medication should not be used in patients with type 1 diabetes or diabetic ketoacidosis, and patients who have had severe allergic reactions to this drug or its components should avoid it. Patients with impaired kidney function may experience delayed excretion of this medication, so they should take a lower dose than prescribed by their doctor and have regular kidney function tests. There is a risk of hypoglycemia when used alone or in combination with other diabetes medications, so if symptoms of hypoglycemia such as dizziness, cold sweat, or tremor occur, appropriate measures should be taken immediately. Symptoms such as headaches, upper respiratory infections, nasopharyngitis, diarrhea, and abdominal pain may occur during treatment. If these symptoms are severe or persistent, consulting a doctor is recommended. Safety during pregnancy has not been established, so pregnant women should avoid using this medication, and nursing women should also refrain from its use, as this medication may be secreted in breast milk. Safety and effectiveness in children and adolescents under 18 years of age have not been adequately studied, so its use in this age group is not recommended. Elderly patients are more likely to have decreased kidney function, which may require dosage adjustments; therefore, it is important to undergo regular kidney function tests during treatment. In case of overdose, seek medical treatment immediately, as this medication can be partially removed by hemodialysis, and dialysis treatment may be considered in severe overdose cases. If symptoms such as joint pain or skin blistering appear while taking this medication, inform a doctor immediately and stop taking it.

Serious side effects

Hives, severe swelling (angioedema), severe allergic reactions, anaphylaxis, severe hypersensitivity reactions, Stevens-Johnson syndrome, exfoliative skin disease, severe rash with fever, blistering, skin peeling, mucosal pain in mouth/eyes, severe skin reactions, difficulty breathing, respiratory issues, acute pancreatitis, fatal/non-fatal hemorrhagic or necrotizing pancreatitis, liver abnormalities (jaundice), acute renal failure, severe and disabling

Mild side effects

• Headache
• upper respiratory infection
• nasopharyngitis
• diarrhea
• nausea
• abdominal pain
• constipation
• vomiting
• myalgia
• limb pain

This medication should be stored in a tightly sealed container to prevent air and moisture from entering. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

Orange, round, biconvex film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP x 3)]