Hyphet Tablet 3 mg (Donepezil Hydrochloride Monohydrate)

Adult dose

As Donepezil Hydrochloride, administer 5 mg once daily before bedtime. For 4-6 weeks, administer 5 mg and it can be increased to 10 mg after clinical response. To reduce gastrointestinal adverse reactions, the initial dosage may begin at 3 mg once daily if necessary, but should not exceed 1-2 weeks. Underweight female patients aged over 85 years should not exceed 5 mg daily and require careful monitoring.

Child dose

There is no experience in using this medication in children.

This medication contains Donepezil Hydrochloride Monohydrate as its main ingredient and is used for treating symptoms of Alzheimer's disease. This medication should not be used in certain patients. For example, individuals who have an allergy to this medication or its components, pregnant women or women who may become pregnant, and patients with lactose intolerance or specific genetic metabolic disorders should not take this medication. Patients with heart disease or cardiac conduction disorders should exercise caution when using this medication, as it can slow the heart rate or cause arrhythmias. Additionally, patients with a history of peptic ulcers or those taking non-steroidal anti-inflammatory drugs should be cautious as there may be an increased risk of gastrointestinal bleeding or worsening of ulcers. Patients with asthma or chronic obstructive pulmonary disease (COPD) may also experience worsening symptoms while using this medication, so it should be administered with care. Patients who have extrapyramidal symptoms, such as those with Parkinson's disease, should be careful as this medication may worsen their symptoms. While taking this medication, various side effects may occur. For example, issues related to the heart (bradycardia, heart block, heart failure, etc.), gastrointestinal problems (nausea, vomiting, diarrhea, gastrointestinal bleeding, etc.), liver function abnormalities, nervous system issues (seizures, extrapyramidal symptoms, hallucinations, etc.), respiratory distress, acute pancreatitis, acute renal failure, sudden death have been reported. Additionally, various side effects such as insomnia, dizziness, headache, fatigue, myalgia, rash, blood abnormalities, etc., may occur; therefore, if abnormal symptoms appear, you should consult a healthcare professional immediately. This medication is approved only for patients with Alzheimer's disease and should not be used for other forms of dementia or memory disorders. During treatment, the patient's condition should be regularly assessed to ensure the medication's effectiveness, and if it is ineffective, treatment may be discontinued. Patients with cardiovascular disease should have their heart conditions monitored through an electrocardiogram. This medication may affect driving or operating machinery; therefore, caution is required during the initial stages of treatment or when changing dosages. Pregnant or nursing women are advised not to use this medication, and if necessary, they should consult a physician. Safety in pediatric patients has not been established, so it should not be used in children. This medication may affect liver and kidney function; therefore, regular clinical tests to verify liver and kidney functionality are recommended. In cases of overdose, serious symptoms such as nausea, vomiting, bradycardia, respiratory depression may occur, and one should visit a medical institution immediately for appropriate treatment. Lastly, this medication should be stored out of reach of children, and it is advisable not to transfer it to another container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blistering, peeling skin, pain in the mucous membranes of the mouth/eyes, difficulty or struggle to breathe, asthma attacks, cough with fever and respiratory disturbances, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headache, seizures, disorientation, visual disturbances, paralysis, urination

Mild side effects

• Anorexia
• hallucinations
• agitation
• aggressive behavior
• anxiety disorders
• insomnia
• drowsiness
• increased libido
• talkativeness
• mania

This medication should be stored in a tightly closed container to prevent air intrusion, at room temperature between 1°C and 30°C. Proper storage preserves the medication's effectiveness and prevents deterioration.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle