Abiraterone Tablet 500mg (Abiraterone Acetate (Unrefined))

Adult dose

The recommended dosage for this medication is 1,000mg (2 tablets of 500mg) once daily and it must be taken on an empty stomach. It should be taken at least 2 hours after a meal and no food should be consumed for at least 1 hour after taking it. The tablet should be swallowed whole with water. In cases of liver impairment, the dose is reduced to 500mg (1 tablet) once daily, and it should not be taken with food. Monitoring is required for re-treatment.

This medication should not be used in women who are pregnant or may become pregnant. Individuals who have an allergic reaction to this medication should also not take it. It should not be administered to patients receiving radium-223 chloride in combination. Patients with mineralocorticoid excess symptoms such as hypertension, hypokalemia, and fluid retention should be cautious when taking this medication. Blood pressure, serum potassium, and fluid status should be monitored regularly, especially in patients with heart disease. Patients with impaired liver function should frequently undergo liver function tests before and during treatment with this medication, and the use of this medication must be stopped immediately if liver function worsens severely. This medication should not be used in patients with severe liver impairment. Adverse effects of this medication may include hypertension, hypokalemia, fluid retention, edema, urinary tract infection, fatigue, joint swelling/discomfort, constipation, diarrhea, dyspepsia, facial flushing, cough, insomnia, bruising, falls, upper respiratory infection, rhinitis, hematuria, rash, back pain, limb pain, bone pain, flank pain, spinal osteoarthritis, joint swelling, spinal foramen stenosis, weakness, facial swelling, pain, chest pain, chest discomfort, mucosal inflammation, dizziness, headache, and sensory disturbances. Patients with cardiovascular disease or decreased heart function should exercise particular caution when using this medication. This medication should be taken on an empty stomach, as taking it with food may increase absorption and safety and efficacy have not been established. It may interact with other medications, especially those metabolized by the liver; consultation with a doctor or pharmacist is advised when taking other drugs. The safety of this medication has not been established in pregnant or nursing women, and men who are sexually active with women of childbearing age should take precautions to prevent pregnancy, such as using condoms. This medication is not intended for use in children. In the case of overdose, medication should be stopped immediately, and cardiac status and liver function should be monitored in a hospital setting. Store this medication out of reach of children and in its original container.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities with cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, vision abnormalities, paralysis, significant decrease in urine output.

Mild side effects

• Hypokalemia
• hypertension
• peripheral edema
• urinary tract infection
• fatigue
• joint swelling/discomfort
• constipation
• diarrhea
• dyspepsia
• facial flushing

This medication should be stored in a tightly sealed container, protected from air and light, and it is safe to store at a temperature between 1 to 30 degrees Celsius. Storing this way will help maintain the medication's effectiveness and prevent degradation.

Appearance

Pink oval film-coated tablet

Package unit

56 tablets/box [14 tablets/PTPX4]