Sitaplus Tablet 50/500 mg (Sitagliptin, Metformin)

Adult dose

This medication is generally taken twice a day with food. The initial dose is determined based on the patient's current treatment regimen. 1. For patients not currently treated with metformin: The initial dose is one tablet of this medication 50/500 mg taken twice a day, and may be titrated to one tablet of 50/1000 mg taken twice a day. 2. For patients receiving metformin therapy: The recommended initial dosage is

This medication contains sitagliptin and metformin and is used for the treatment of type 2 diabetes. During the use of this medication, allergic reactions may occur; if symptoms such as skin rash, hives, or difficulty breathing appear, discontinue use immediately and consult a physician. Acute pancreatitis, a serious inflammation of the pancreas, may occur, so if symptoms such as abdominal pain, nausea, vomiting, or fever arise, inform medical personnel promptly. This medication should not be used in patients with severe renal impairment or in acute disease states. Patients with decreased kidney function should use this medication cautiously and undergo regular kidney function tests. It is safer for pregnant women or those who may become pregnant, and nursing mothers not to take this medication. This medication can cause hypoglycemia, so blood sugar levels should be monitored closely, especially when taken with insulin or sulfonylurea medications. Rare but very serious metabolic disorders, such as lactic acidosis, may occur; symptoms such as muscle pain, weakness, difficulty breathing, abdominal pain, and changes in consciousness require immediate hospital visits. Alcohol consumption may increase the risk of lactic acidosis, thus it's advisable to avoid drinking during the use of this medication. If undergoing surgery, stop taking this medication 48 hours before the procedure, and resume after the oral intake has recovered to normal and kidney function is confirmed. This medication contains coloring agents, so patients with a history of allergy to such components should be cautious. Safety and efficacy in children and adolescents under 18 years of age have not been sufficiently confirmed, so its use is not recommended. Elderly patients may have decreased kidney function, necessitating dosage adjustments and regular monitoring of renal function. In cases of overdose, immediate medical attention should be sought, and if necessary, blood dialysis may be used to remove the drug. Regular blood sugar checks and ongoing assessments of kidney function and hematological tests during the use of this medication are important.

Serious side effects

• Hives
• angioedema
• chest tightness
• difficulty breathing
• anaphylaxis
• rash
• cutaneous vasculitis
• Stevens-Johnson syndrome
• severe skin adverse reactions
• acute pancreatitis

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• upper respiratory tract infection
• headache
• nasopharyngitis
• constipation
• muscle pain
• limb pain

This medication should be stored in a tightly sealed container to prevent air and moisture exposure, ideally at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness.

Appearance

Bright pink oval film-coated tablet

Package unit

Bottle - 100 tablets/bottle, Bottle - 30 tablets/bottle