Sitaplus Tablet 50/850 mg (Sitagliptin, Metformin)

Adult dose

This medication is generally taken twice a day with food and the dosage is gradually increased to reduce gastrointestinal side effects caused by Metformin. 1. Patients not treated with Metformin: The initial dose is 1 tablet (50/500 mg) twice daily, which may be increased to 50/1000 mg. 2. Patients already undergoing Metformin treatment: Sitagliptin 50 mg is taken twice daily (total of 100 mg).

This medication is composed of two active ingredients, Sitagliptin and Metformin, and is primarily used for the treatment of type 2 diabetes. While taking this medication, severe allergic reactions may occur; therefore, if symptoms such as skin rash or difficulty breathing arise, discontinue use immediately and consult a doctor. Additionally, there is a risk of serious pancreatic inflammation known as pancreatitis; if sudden abdominal pain, nausea, or vomiting occurs, inform medical personnel immediately. Although rare, the Metformin component can cause lethal metabolic acidosis known as lactic acidosis; this medication should not be taken if there is severe dehydration, kidney function impairment, or serious infections. This drug should not be administered to patients with moderate to severe renal impairment, acute heart failure, or acute myocardial infarction, and use should be temporarily suspended before and after tests involving iodine contrast agents. It is advisable not to use this medication in pregnant or nursing women or in children under 18 years of age. During treatment, regular meals and exercise should be maintained for blood glucose control, and regular blood tests and kidney function tests should be performed. Hypoglycemic symptoms may occur, so especially when taken in conjunction with other blood glucose-lowering agents, caution should be exercised for hypoglycemic symptoms. If symptoms occur, sugar should be taken immediately. Alcohol consumption may increase the risk of lactic acidosis; therefore, it is best to avoid drinking while taking this medication. If surgery is imminent or severe infections, trauma, etc., occur, the administration of this medication should be temporarily discontinued and resumed only after the patient's condition stabilizes. This medication contains certain coloring agents; caution should be exercised if allergic reactions to these exist. Finally, if any unusual symptoms or discomfort occur during the use of this medication, it is essential to consult a doctor or pharmacist immediately for appropriate measures.

Serious side effects

Urticaria, severe swelling (angioedema), chest tightness, difficulty breathing, anaphylaxis, Stevens-Johnson syndrome, severe skin adverse reactions, acute pancreatitis, acute renal failure, acute and severe renal function deterioration, lactic acidosis, severe hypoglycemia, severe edema, rhabdomyolysis, acute pancreatitis, severe rash, seizures, confusion, visual disturbances, paralysis, severe arthralgia with disabilities, bullous pemphigoid, acute renal failure

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• upper respiratory infection
• nasopharyngitis
• headache
• hypoglycemia
• myalgia
• limb pain

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. It is best to maintain the storage temperature between 1 degree and 30 degrees Celsius to preserve the medication's effectiveness for a longer duration.

Appearance

Pink oval film-coated tablet

Package unit

Bottle - 100 tablets/bottle, Bottle - 30 tablets/bottle