Boseitin Tablet 20mg (Botioxetine Hydrochloride)

Adult dosage

1. Adults The initial and recommended dose of this drug is 10mg once daily. Depending on the patient's response, the dose may be increased to a maximum of 20mg once daily or reduced to a minimum of 5mg once daily. This drug may be taken with or without food. 1) Maintenance treatment To ensure a therapeutic effect, drug treatment is recommended for at least 6 months even after depressive symptoms have resolved. 2) Discontinuation This drug may be discontinued immediately without the need for gradual dose reduction. 2. Administration to elderly patients For elderly patients aged 65 years or older, the initial dose is 5mg once daily. If this drug is administered at doses of 10mg or more once daily, treatment should be given with caution. 3. Administration with cytochrome P450 inhibitors and inducers 1) Cytochrome P450 inhibitors When this drug is coadministered with potent cytochrome P450 inhibitors (e.g., bupropion, quinidine, fluoxetine, paroxetine, etc.), reduce the dose of this drug depending on the patient's response (see Section 6. Drug Interactions). 2) Cytochrome P450 inducers When this drug is coadministered with broad-spectrum cytochrome P450 inducers (e.g., rifampicin, carbamazepine, phenytoin, etc.), the dose of this drug may be adjusted depending on the patient's response (see Section 6. Drug Interactions). 4. Administration with monoamine oxidase inhibitors (MAOIs) 1) Switching from MAO inhibitors used to treat psychiatric disorders When discontinuing an MAO inhibitor used to treat a psychiatric disorder and initiating treatment with this drug, an interval of at least 14 days must be allowed. Conversely, at least 14 days must elapse after discontinuing this drug before initiating an MAO inhibitor to treat a psychiatric disorder. 2) Other MAO inhibitors, such as linezolid or methylene blue Patients should be monitored for symptoms of serotonin syndrome for 2 weeks after receiving linezolid or intravenous methylene blue, or for 24 hours after the last dose, whichever occurs first. Treatment with this drug may be restarted 24 hours after the last dose of linezolid or intravenous methylene blue. The risk associated with methylene blue administered by nonintravenous routes (oral tablets or local injection), or with intravenous administration of this drug at a dose of 1mg/kg or less, is unclear.

This medication is primarily used to improve symptoms associated with depression. During the use of this medication, there may be an increased risk of suicidal thoughts or behaviors, especially in children, adolescents, and young adults, so careful monitoring by a physician is necessary for patients in this age group. Serotonin syndrome, a serious side effect, may occur, so special caution is required when taking it with other serotonergic medications. This medication should not be taken with certain drugs, particularly MAO inhibitors, as drug interactions may increase the risk of side effects. Caution should be exercised when administering to patients with a history of seizures, significantly impaired liver or kidney function, bleeding tendencies, and the elderly. During initial use, side effects such as nausea, dizziness, insomnia, and decreased appetite may occur, but these are mostly transient symptoms. If this medication is discontinued suddenly, withdrawal symptoms such as dizziness, sweating, and malaise may occur, so it is important to gradually reduce the dosage according to the physician's instructions when stopping. If you are pregnant or breastfeeding, this medication may affect the fetus or newborn, so it must be taken only after consultation with a physician. The safety and efficacy of this medication in children and adolescents have not been sufficiently established and are not recommended. Extra caution may be needed when driving or operating hazardous machinery due to the effects of this medication. In case of overdose, symptoms such as nausea, dizziness, and diarrhea may occur, and immediate medical attention should be sought.

• Suicidal impulses
• suicidal tendencies
• anxiety
• hallucinations
• delirium
• coma
• tachycardia
• unstable blood pressure
• dizziness
• sweating

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is recommended to maintain the storage temperature between 1 degree and 30 degrees Celsius at room temperature. This will help safely preserve the effectiveness of the medication.

Appearance

reddish-brown oblong film-coated tablet

Package unit

200 tablets/bottle