Medication info
Colostatin 2.5 mg (Rosuvastatin Calcium)

Colostatin 2.5 mg (Rosuvastatin Calcium)

Prescription medicationTablet
Ingredient · strength
Rosuvastatin Calcium›2.6mg / 1 tablet
Manufacturer / importer
신풍제약(주)
Appearance
White round film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 202301094 · Approved 2023.03.31 · Insurance code 648508240

Summary

Main use
Improvement of hypercholesterolemia and hyperlipidemia
Who uses it
Adults
Adult dosage
This medication is initiated at a dose of 2.5 or 5 mg once daily, and maintenance doses can be adjusted for further LDL-cholesterol reduction needs. The maintenance dose is 10 mg once daily, and it can be increased to a maximum of 20 mg based on LDL-cholesterol levels and patient response at intervals of 4 weeks or more. It can be administered at any time during the day, regardless of meals, with considerations for renal failure, liver failure patients, and the elderly.

Ingredients

Manufacturer
신풍제약(주)

Efficacy & effects

Improvement of hypercholesterolemia and hyperlipidemia

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • mixed hyperlipidemia
View approved original text

This medication is used for the treatment of primary hypercholesterolemia and mixed hyperlipidemia. Specifically, it is applicable to patients with type IIa and type IIb hyperlipidemia, including heterozygous familial hypercholesterolemia. It is used to supplement dietary therapy when not controlled by diet and exercise. This medication helps lower blood cholesterol levels, reducing the risk of cardiovascular disease. Regular use improves blood lipid levels and supports the maintenance of patient health. Therefore, it is effectively used in the treatment of hyperlipidemia.

Dosage and Administration

Adult dosage

This medication is initiated at a dose of 2.5 or 5 mg once daily, and maintenance doses can be adjusted for further LDL-cholesterol reduction needs. The maintenance dose is 10 mg once daily, and it can be increased to a maximum of 20 mg based on LDL-cholesterol levels and patient response at intervals of 4 weeks or more. It can be administered at any time during the day, regardless of meals, with considerations for renal failure, liver failure patients, and the elderly.

Precautions

This medication should not be administered to certain patients. For example, individuals who are allergic to any of its components, those with severely impaired liver function, or those with muscle diseases should avoid it. Additionally, patients with significantly reduced kidney function and women who are pregnant or breastfeeding should not take this medication. This medication contains lactose, making it unsuitable for patients with genetic metabolic disorders such as lactose intolerance. While using this medication, liver function and muscle condition should be carefully monitored. Individuals with a history of liver disease or who consume alcohol excessively should have regular liver enzyme tests. If symptoms of muscle pain or weakness occur, immediate notification to medical personnel is essential, and discontinuation of the medication may be necessary. This medication can interact with other drugs, so it is crucial to inform your healthcare provider of any other medications being taken. In particular, the risk of muscle-related adverse reactions may increase when used with certain antibiotics, antifungals, immunosuppressants, or fibrates. Women of childbearing potential are advised to use proper contraception while taking this medication and to discontinue use immediately if pregnancy occurs. During breastfeeding, it is recommended to avoid using this medication as it may be passed into breast milk. In cases of overdose, there is no specific antidote, so treatment should be symptomatic, monitoring liver function and muscle enzyme levels. Caution is needed as dizziness may occur when driving or operating machinery.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, mucosal pain in the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities with cough and fever, yellowing of skin or eyes (jaundice), severe overall lethargy, sudden and very severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination issues

Mild side effects

  • Dyspepsia
  • pruritus
  • headache
  • dizziness
  • constipation
  • nausea
  • abdominal pain
  • diabetes
  • rash
  • myalgia
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  • weakness
  • hematuria
  • diarrhea
  • itching
  • abnormal liver function tests
  • fainting
  • generalized pain
  • muscle cramps
  • gout
  • erectile dysfunction
  • fatigue
  • numbness
  • paresthesia
  • chest discomfort
  • loss of appetite
  • abdominal distension
  • joint pain
  • memory loss
  • peripheral neuropathy
  • cough
  • thrombocytopenia
  • hepatitis
  • increased transaminases
  • lichenoid drug rash
  • lupus-like symptoms

Not everyone experiences these, and they can vary from person to person.

Storage

This medication must be stored in a tightly closed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 to 30 degrees Celsius.

Appearance and packaging

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.