Univex Capsule 100 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medication should be adjusted according to the patient and may be administered without regard to meals. ○ Adults 1. Osteoarthritis (degenerative arthritis) : Take celecoxib 200 mg once daily, or 100 mg twice daily. 2. Rheumatoid arthritis : Take celecoxib 100 mg or 200 mg twice daily. 3. Ankylosing spondylitis (AS) : Administer celecoxib 200 mg once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks at 400 mg daily, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea : The recommended initial dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment : In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be consulted with a doctor or pharmacist if taken by individuals who consume more than three glasses of alcohol regularly each day due to the risk of gastrointestinal bleeding. This medication may increase the risk of cardiovascular thrombotic events, myocardial infarction, and stroke, so it should only be used at the lowest effective dose for the shortest duration possible. Even in patients without a history of cardiovascular disease, symptoms should be monitored closely. This medication can cause serious gastrointestinal adverse reactions such as gastrointestinal perforation, ulcers, and bleeding, and the risk is higher, especially in the elderly. If symptoms such as gastrointestinal bleeding or pain occur during treatment, healthcare personnel should be notified immediately. This medication should not be given to patients with specific allergies, liver or kidney disease, cardiovascular disease, inflammatory bowel disease, etc., and should be avoided by women who are pregnant or breastfeeding. Patients with impaired liver or kidney function, asthma, or hypertension should use this medication with caution, and if unusual symptoms occur during treatment, they should consult a doctor immediately. Various adverse reactions have been reported with this medication, with common symptoms including dyspepsia, headache, dizziness, edema, hypertension, rash, etc., as well as severe skin reactions or liver function abnormalities. Before taking this medication, the possibility of interactions with other medicines should be confirmed, especially if combined with drugs metabolized in the liver. Pregnant women or women who may become pregnant should not take this medication, and if taken during pregnancy, it should be discontinued due to potential effects on the fetus. This medication has not established safety and efficacy in children and adolescents under 18 years of age, thus it is advisable not to use it. Elderly patients may have reduced kidney, liver, and heart function, thus special monitoring is needed during treatment. Patients taking this medication for an extended period should undergo regular blood tests as well as liver and kidney function tests, and if any abnormal signs occur, the medication should be stopped. In case of overdose, symptoms such as lethargy, drowsiness, nausea, vomiting, and gastrointestinal bleeding may occur, and immediate medical attention should be sought for appropriate treatment. Keep out of reach of children, and transferring medications to other containers should be avoided due to the risk of accidents and degradation in quality.

Gastrointestinal bleeding, cardiovascular thromboembolic reactions, myocardial infarction, stroke, upper and lower gastrointestinal perforation, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, delirium, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, indigestion, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, angioedema, alopecia, bullous dermatitis, peripheral edema, facial edema, influenza-like illness, damage, headache, leg cramps, hypertonia, sensory loss, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, allergy exacerbation, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylaxis-like reaction, angioedema, loss of appetite, increased appetite, depression, neurosensitivity, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory tract infection, bronchospasm, exacerbating bronchospasm, dyspnea, laryngitis, pneumonia, nosebleed, voice disorders, vesicular dermatitis, dermatitis, nail disease, photosensitivity reaction, pruritus, erythematous rash, papular rash, skin disease, skin dryness, increased sweating, erythema multiforme, exfoliative dermatitis, skin and mucous membrane syndrome, toxic epidermal necrolysis, eczema, lipoma, drug rash, arrhythmia, ventricular hypertrophy, angina, unstable angina, coronary artery disease, myocardial infarction, heart failure, palpitations, tachycardia, aortic valve insufficiency, hematoma, bradycardia, syncope, ventricular fibrillation, pulmonary embolism, cerebrovascular accident, peripheral gangrene, thrombotic venous inflammation, vasculitis, deep vein thrombosis, cerebral hemorrhage, mononeuropathy, wound infection, gingivitis, herpes simplex, shingles, bacterial infection, fungal infection, soft tissue infection, viral infection, candidiasis, genital candidiasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, thoracic neoplasm, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased serum sodium, increased serum potassium, increased BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthrosis, skeletal abnormalities, myalgia, cervical tension syndrome, synovitis, tendinitis, myositis, fracture, tendon rupture, pain in various regions, muscle rigidity, decreased hematocrit, increased hemoglobin, nosebleed, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, borreliosis, contact dermatitis, injection site reaction, skin nodules, taste disorder, albuminuria, cystitis, hematuria, dysuria, polyuria, kidney stones, urinary incontinence, urinary tract infection, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, anaphylactic reaction, cerebral hemorrhage, pulmonary embolism, interstitial pneumonia, liver failure, fulminant hepatitis, liver necrosis, biliary stasis, biliary stasis hepatitis, photosensitivity reaction, Stevens-Johnson syndrome, acute generalized pustular exanthema, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change glomerulonephritis, female infertility

This medication should be stored in a tightly closed container to prevent air from entering, and it is best kept in a cool place between 15 to 30 degrees Celsius. Proper storage will help maintain the drug's effectiveness and prevent degradation.

Appearance

A white capsule filled with a white to light yellow powder with a blue stripe on the upper and lower parts.

Package unit

30 capsules/bottle, 100 capsules/bottle