Sitagliptin Duo Tablet 50/1000 mg

Adult dose

This medication is generally taken twice a day with meals, and the dosage is gradually increased to reduce gastrointestinal adverse reactions caused by metformin. 1. For patients not currently treated with metformin: Take this medication 50/500 mg twice a day, 1 tablet at a time; it can be increased to 50/1000 mg twice a day, 1 tablet at a time. 2. For patients currently being treated with metformin:

This medication contains sitagliptin and metformin, which help manage blood glucose levels. First, be aware of allergic reactions when taking this medication. If symptoms such as skin rash or difficulty breathing occur, discontinue use immediately and consult a physician. Additionally, pancreatitis may occur, so if you experience abdominal pain, vomiting, or severe abdominal discomfort while taking this medication, visit a hospital immediately. This medication may pose risks for patients with impaired kidney function, so the decision to take it should be based on kidney function test results, and it should be discontinued if kidney function deteriorates suddenly. Patients with heart diseases or heart failure should definitely consult a doctor before using this medication. Particularly, if receiving iodinated contrast agents for radiological examinations, this medication should be temporarily discontinued before and after the tests, and it should only be resumed after confirming normal kidney function. It is safer not to take this medication if you are pregnant, may become pregnant, or are breastfeeding. This medication may cause hypoglycemia, so be sure to monitor blood glucose levels if you skip meals or eat irregularly, engage in strenuous exercise, or use it in conjunction with other blood sugar-lowering medications. Avoid alcohol consumption while on this medication, and temporarily discontinue use if you have issues with liver or kidney function, dehydration, infections, or severe trauma. Regular blood tests and kidney function tests should be performed, and supplementation may be needed if vitamin B12 levels drop. Close monitoring of kidney function is required when administering this medication to elderly patients, and dosing adjustments may be necessary. If you experience severe joint pain or skin blistering while taking this medication, inform your physician immediately. In case of overdose, seek medical attention immediately, as some components may be removed via hemodialysis. Finally, this medication may interact with various drugs, so if you are using other medications, inform your physician or pharmacist, as the risk of hypoglycemia may increase when combined with other blood sugar-lowering agents.

Serious side effects

• rash
• angioedema
• anaphylaxis
• dermatitis
• vasculitis
• Stevens-Johnson syndrome
• exfoliative skin disease
• acute pancreatitis
• acute renal failure
• dyspnea

Mild side effects

• diarrhea
• nausea
• vomiting
• abdominal pain
• upper respiratory tract infection
• pharyngitis
• headache
• hypoglycemia
• constipation
• weakness

Store this medication in a tightly sealed container to prevent air or moisture from entering. It is recommended to maintain the storage temperature between 1 and 30 degrees Celsius. Proper storage will ensure the safety and effectiveness of the medication.

Appearance

reddish-brown oval film-coated tablet

Package unit

bottle - 100 tablets/bottle, bottle - 30 tablets/bottle