Sitagliptin-Metformin Duo 50/500 mg

Adult dose

This medication is generally taken 2 times a day with food, with a gradual increase in dosage to reduce gastrointestinal side effects from metformin. 1. For patients not currently treated with metformin: Start with an initial dose of this medication 50/500 mg, 1 tablet twice a day, and it can be increased to 50/1000 mg, 1 tablet twice a day. 2. For patients treated with metformin,

This medication contains sitagliptin and metformin and is used for diabetes treatment. First, serious allergic reactions may occur while taking this medication, so if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck appear, immediately stop use and consult a doctor. Additionally, there is a risk of acute pancreatitis, which is inflammation of the pancreas, so if symptoms such as abdominal pain, vomiting, or severe abdominal discomfort arise, inform medical personnel immediately. The metformin component in this drug can cause a rare but life-threatening side effect called lactic acidosis, so seek immediate treatment if symptoms such as shortness of breath, muscle pain, fatigue, or abdominal pain occur. Patients with poor kidney function, dehydration, severe infection, heart disease, or liver disease should avoid taking this medication for safety reasons. It is advisable to temporarily discontinue this medication before and after examinations using iodine contrast media and to resume only after confirming normal kidney function. Pregnant women, women who may become pregnant, and breastfeeding women should not take this medication. This drug should be administered with caution to patients with irregular meals, intense exercise, or a history of certain allergies. There may be side effects such as diarrhea, nausea, vomiting, headache, and upper respiratory infections during the course of treatment, so if symptoms are severe, consult a doctor. When taken with other blood sugar-lowering medications or insulin, the risk of hypoglycemia may increase, so blood sugar levels should be monitored frequently, and medication dosage adjusted if necessary. During treatment, regular checks of kidney function, blood tests, and vitamin B12 levels should be performed to ensure there are no abnormalities. Alcohol consumption can increase the risk of lactic acidosis, so it is important not to drink excessively while taking this drug. If surgery is planned, discontinue this medication 48 hours before the procedure and only resume after confirming that kidney function has returned to normal afterwards. Lastly, this medication is not advised for children under 18 years or those under 10 years of age as safety and efficacy have not been established.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor (severe allergic reactions), severe rash with fever, blisters, skin peeling, oral/ocular mucosal pain (severe skin adverse reactions), shortness of breath or difficulty breathing, asthma attack, cough with fever accompanying respiratory issues (respiratory problems), yellowing of skin or eyes (jaundice), profound fatigue (liver issues), sudden

Mild side effects

• Diarrhea
• upper respiratory infection
• headache
• nausea
• vomiting
• abdominal pain
• constipation
• nasopharyngitis
• asthenia
• decreased appetite

This medication should be stored in a tightly sealed container to prevent air or moisture from entering, and it is best kept at room temperature between 1 degree and 30 degrees Celsius. By storing it this way, the efficacy of the medication can be well maintained.

Appearance

Bright pink oval film-coated tablet

Package unit

Bottle - 100 tablets/bottle, Bottle - 30 tablets/bottle